Results 61 to 70 of about 6,444 (174)

Toward Precision Medicine: Gene Therapy Applications in the Management of Uveal Melanoma

open access: yesCancer Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background Uveal melanoma (UM) is the prevailing malignant tumor that develops within the eye in adults, and it has a bleak outlook because of the few treatment choices available and the high likelihood of returning after treatment. Currently, surgical intervention, radiation therapy, and a combination of both modalities are available ...
Alireza Azani   +13 more
wiley   +1 more source

The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly. [PDF]

open access: yes, 2015
It is unknown whether the mammalian cell cycle could impact the assembly of viruses maturing in the nucleus. We addressed this question using MVM, a reference member of the icosahedral ssDNA nuclear parvoviruses, which requires cell proliferation to ...
Almendral, JM   +5 more
core   +7 more sources

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

open access: yesAdvanced Genetics, Volume 6, Issue 4, December 2025.
This article examines how the respiratory virome contributes to health and disease, highlighting its interactions with the host and bacteriome. Key disease associations and present knowledge gaps are outlined. The review discusses challenges in sample collection and preprocessing, and presents future research directions for understanding virome ...
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
wiley   +1 more source

Alcohol‐Related Liver Disease and Metabolic Dysfunction‐Associated Steatotic Liver Disease: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Alcohol‐related (ALD) and metabolic dysfunction‐associated (MASLD) steatotic liver disease, while initiated by distinct etiologies (ethanol vs. metabolic stress), converge on shared core pathogenic pathways that drive progression. These include dysregulated lipid metabolism, programmed cell death, cellular senescence, gut dysbiosis, and immune ...
Yupin Tan   +3 more
wiley   +1 more source

Genetic characterization of parvoviruses circulating in turkey and chicken flocks in Poland [PDF]

open access: yes, 2012
Between 2008 and 2011, commercial turkey and chicken flocks in Poland were examined for the presence of turkey parvovirus (TuPV) and chicken parvovirus (ChPV).
Anna Jacukowicz   +3 more
core   +1 more source

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

open access: yesPediatric Discovery, Volume 3, Issue 4, December 2025.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao   +6 more
wiley   +1 more source

El Bocavirus humano: un nuevo virus respiratorio Human bocavirus: a new respiratory virus

open access: yesIatreia, 2006
Las infecciones respiratorias agudas son una causa muy importante de morbilidad y mortalidad, especialmente en los niños y en los países en desarrollo.
Carlos Aguirre Muñoz
doaj  

Human Bocavirus Infection Markers in Peripheral Blood and Stool Samples of Children with Acute Gastroenteritis

open access: yesViruses, 2018
Human bocaviruses (HBoVs) 1⁻4 belong to the Parvoviridae family, and they infect the respiratory or gastrointestinal tracts in children. We investigated the prevalence of HBoV1⁻4 DNAs in the blood and stool samples, and of HBoV1⁻4 IgG ...
Zaiga Nora-Krukle   +8 more
doaj   +1 more source

Outbreak tracking of Aleutian mink disease virus (AMDV) using partial NS1 gene sequencing [PDF]

open access: yes, 2017
Background Aleutian Mink Disease (AMD) is an infectious disease of mink (Neovison vison) and globally a major cause of economic losses in mink farming. The disease is caused by Aleutian Mink Disease Virus (AMDV) that belongs to the genus Amdoparvovirus ...
Chriél, Mariann   +6 more
core   +1 more source

Bumble Bees and Honey Bees on Islands Harbour Reduced Viral Species Richness, Yet Honey Bee Populations Are Dominated by a Deformed Wing Virus Recombinant

open access: yesMolecular Ecology, Volume 34, Issue 24, December 2025.
ABSTRACT Pollinators harbour diverse RNA viromes that play a vital role in their health. Yet, factors that shape viral communities are often unclear. The European honey bee (Apis mellifera) is experiencing a viral epidemic since the emergence of the parasitic mite Varroa destructor (varroa) introduced vector‐borne transmission, which has also been ...
Jana Dobelmann, Lena Wilfert
wiley   +1 more source

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