Results 91 to 100 of about 1,240,534 (281)
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Latinos, African Americans and the Coalitional Case for a Federal Jobs Program [PDF]
, 2012 In the late 1970s, amidst growing unemployment in black and Latino communities, the newly-formed Congressional Hispanic Caucus (CHC) supported the Congressional Black Caucus (CBC) in its call for full employment in the run up to the passage of the ...
Aja, Alan A. +2 more
core +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
FASB: Making Financial Statements Mysterious [PDF]
, 2008 Since the passage of the Sarbanes-Oxley Act in 2002, the Financial Accounting Standards Board has passed rules that it promises will make corporate accounting more transparent.
T. J. Rodgers
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Expanding Resources for Service: Strategies from State Commissions [PDF]
, 1997 In response to the passage of the National and Community Service Trust Act in 1993, state-level Commissions were created to direct federal funds to local service programs, monitor program progress and quality, and to determine the content and direction ...
Kathryn Furano, Linda Z. Jucovy
core
El olvido de lo que fundó el acto
Desde el Jardín de Freud, 2009 Resumen El acto que consiste en asumir la posición del analista es un momento crucial de la cura, denominado por Lacan el pase. La autora muestra que se trata de no olvidar este momento, porque es la causa del deseo del analista. Podemos constatar, en la
Isabelle Morin
doaj +2 more sources
The New Virtual Crackdown on Sex Workers’ Rights: Perspectives from the United States
Anti-Trafficking Review, 2019 On 11 April 2018, the Fight Online Sex Trafficking Act (FOSTA) was signed into law in the United States. FOSTA introduced new provisions to amend the Communications Act of 1934 so that websites can be prosecuted if they engage ‘in the promotion or ...
Meghan Peterson +2 more
doaj +1 more source
Innovative implementation of the Endangered Species Act to improve wildlife passage
, 2001 U. S. Highway 12 is a major highway located in North Central Idaho. It bisects a primitive, remote area of the Clearwater National Forest and is adjacent to the Selway-Bitterroot Wilderness. Habitat in this area supports a wide variety of species including fisher, bobcat, cougar, wolverine, elk, moose, deer, as well as gray wolf and lynx, which are ...
Davis, Dan, Gray, Mary E.
openaire +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source