Results 71 to 80 of about 1,241,674 (300)

The Clean Air Act Amendments and Firm Investment in Pollution Abatement Equipment [PDF]

open access: yes, 2003
The command-and-control approach to environmental regulation requires that firms install prescribed technologies to meet specified goals. However, environmental regulations change frequently; in addition, the enforcement agency cannot perfectly monitor ...
Amanda I. Lee, James R. Alm
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Taxation of Unemployment Benefits [PDF]

open access: yes, 2005
Unemployment compensation (UC) benefits have been fully subject to the federal income tax since the passage of the Tax Reform Act of 1986 (P.L. 99-514).
Domestic Social Policy Division   +1 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

A low-water crossing impacts Northern Hog Sucker Hypentelium nigricans movement in an Ozark stream

open access: yesJournal of Freshwater Ecology, 2020
Streams are complex systems that rely on connectivity to maintain natural ecological function. Low-water crossings are common in small-intermediate sized streams and can restrict longitudinal movement of fishes.
Jeffrey M. Williams   +2 more
doaj   +1 more source

A survey of estuarine oxygen concentrations in relation to the passage of migratory salmonids [PDF]

open access: yes, 1984
This report presents the first attempt at a national assessment of an Environmental Quality Standard (EQS) for dissolved oxygen (DO) in estuaries with the objective of allowing the passage of migratory salmonids. Under the Control of Pollution Act,
Hugman, S.J., Mance, G., O'Donnell, A.R.
core  

Can the general fraud offence 'get the law right'? Some perspectives on the 'problem' of financial crime [PDF]

open access: yes, 2007
The Fraud Bill, which received Royal Assent on 8 November 2006, created an offence of fraud in English criminal law which marks a departure of utmost significance from the approach adopted hitherto, whereby a number of related offences cover behaviour ...
Wilson, G, Wilson, SJ
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Inhibición y acto. Un recorrido por tenues laberintos del tiempo

open access: yesDesde el Jardín de Freud, 2009
Resumen Este texto cuestiona la oposición radical entre inhibición y acto a partir de una intrincación temporal que nos permite descubrir en la inhibición algo de “la luminosidad del acto” y en el acto, algo de “la inhibición atenta”, aplicada, que exige
Patricia León-López
doaj   +2 more sources

Responding to LGBT forced migration in East Africa

open access: yesForced Migration Review, 2016
Following the passage of Uganda’s Anti-Homosexuality Act in December 2013, hundreds of LGBT individuals fled to Kenya seeking safety. A variety of interventions is needed in both Uganda and Kenya to respond effectively.
Gitta Zomorodi
doaj  

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