Results 91 to 100 of about 1,241,674 (300)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

FASB: Making Financial Statements Mysterious [PDF]

open access: yes, 2008
Since the passage of the Sarbanes-Oxley Act in 2002, the Financial Accounting Standards Board has passed rules that it promises will make corporate accounting more transparent.
T. J. Rodgers
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Antitrust and Regulation [PDF]

open access: yes
Since the passage of the Interstate Commerce Act (1897) and the Sherman Act (1890), regulation and antitrust have operated as competing mechanisms to control competition.
Dennis W. Carlton, Randal C. Picker
core  

The obligatory passage point : abstracting the meaning in tacit knowledge [PDF]

open access: yes, 2013
The lived experience of individuals in the workplace results in an accumulation of dispositions to act. Such dispositions have been termed knowledge [Boisot 1998]. Further, this knowledge is considered to be tacit or explicit [Baumard 1999].
Walton, John
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The New Virtual Crackdown on Sex Workers’ Rights: Perspectives from the United States

open access: yesAnti-Trafficking Review, 2019
On 11 April 2018, the Fight Online Sex Trafficking Act (FOSTA) was signed into law in the United States. FOSTA introduced new provisions to amend the Communications Act of 1934 so that websites can be prosecuted if they engage ‘in the promotion or ...
Meghan Peterson   +2 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

El olvido de lo que fundó el acto

open access: yesDesde el Jardín de Freud, 2009
Resumen El acto que consiste en asumir la posición del analista es un momento crucial de la cura, denominado por Lacan el pase. La autora muestra que se trata de no olvidar este momento, porque es la causa del deseo del analista.
Isabelle Morin
doaj   +2 more sources

The Sex Discrimination Act and its Rocky Rite of Passage

open access: yes, 2010
Through an analysis of the parliamentary debates on the Sex Discrimination Bill 1983–84, this chapter underscores the anxiety that preoccupied the opponents of the Bill. Their fear that the Bill would give rise to a totalitarian regime, reminiscent of an Eastern bloc country, is clearly apparent from their own words.
Thornton, Margaret, Luker, Trish
openaire   +3 more sources

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