Results 61 to 70 of about 1,241,674 (300)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The British-U.S. Memorandum of Understanding of 1986: Implications After Warner [PDF]
This Note argues that the British decision in In re an Inquiry Under the Company Securities (Insider Dealing) Act 1985 (Warner) has impaired British investigatory efforts in securities fraud cases and hampered future American requests for information ...
Colesanti, Scott J.
core +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Addressing the human-centric needs in vehicle scheduling at intersections poses a significant challenge. In this paper, we propose a game scheduling method to address the problem of platoon scheduling while considering priority passage requests. Firstly,
Haiyang Hu, Feng Peng
doaj +1 more source
Gaits are typically classified as walking or running based on kinematics, the shape of the vertical ground reaction force (GRF) curve, and the use of inverted pendulum or spring-mass mechanics during the stance phase.
Hilary M. Clayton, Sarah Jane Hobbs
doaj +1 more source
The Obsolescence of San Antonio v. Rodriguez in the Wake of the Federal Government’s Quest To Leave No Child Behind [PDF]
Since the mid-1950s, a sea change in public education has taken place. Public education—a policy concern traditionally reserved to the states—has become a core concern of the federal government.
Boyce, Sarah G.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Race equality, human rights and mental health legislation: Recent developments in England and Wales
England now has revised mental health legislation following the passage of a mental health Bill through both Houses of Parliament following protracted discussions over seven years.
Lord Patel of Bradford +1 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
In the article I examine whether an act of coming out of an LGBT+ person can be perceived as an existencial equvalent of a religious rite of passage. Paper contains an analysis of fragments of diaries from the collective volume All the Strength I Draw ...
Joanna Anczaruk
doaj +1 more source

