Results 41 to 50 of about 163,378 (254)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
THE RISE AND FALL OF GLASS-STEAGALL
The passage of the Financial Services Modernization Act in 1999 was saidto have finally repealed the Glass-Steagall Act. In 1933, Congress enacted a set of bank regulations entitled of The Banking Act of 1933 (more commonly known as the Glass-Steagall ...
Kenneth Weiher
doaj
Think Tank Soldiers in the Battle for Tax Reform
Contemporary scholars argue that high wealth donors in the U.S. influence political decision making through generous funding of nonprofit organizations like think tanks.
Irvin Renee, Sokolowski Jes
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Comentario sobre Levantar la mano sobre uno mismo, de Jean Améry
Resumen En el libro de Jean Améry (seudónimo de Hans Mayer), Levantar la mano sobre uno mismo. Discurso sobre la muerte voluntaria, el autor utiliza argumentos de orden filosófico y suministra algunos escasos datos autobiográficos (como la ...
Pilar González Rivera
doaj +2 more sources
The Value Effect of Financial Reform on U.K. Banks and Insurance Companies
In response to the financial crisis, a number of reforms to bank regulation have been introduced. Many of these reforms seek to improve the resilience of banks through making changes to their structure.
Teresa Valeria Parise, Vijay Shenai
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Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Addressing the human-centric needs in vehicle scheduling at intersections poses a significant challenge. In this paper, we propose a game scheduling method to address the problem of platoon scheduling while considering priority passage requests. Firstly,
Haiyang Hu, Feng Peng
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

