Results 31 to 40 of about 163,554 (254)

Language of Translation as Seen by Polish Translation Scholars

open access: yesPółrocznik Językoznawczy Tertium, 2016
What Polish translators brought into the theory of translation in the last thirty years merits a synthetic presentation. Here we chose, amidst the “memes of translation” (cf.
Urszula Dąmbska-Prokop
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Insurance barriers to substance use disorder treatment after passage of mental health and addiction parity laws and the affordable care act: A qualitative analysis

open access: yesDrug and Alcohol Dependence Reports, 2022
Introduction: : People who use drugs (PWUDs) in the United States historically have had a higher probability of being uninsured. Passage of the Affordable Care Act, the Paul Wellstone and Pete Domenici Health Parity and Addiction Equity was expected to ...
Julia Dickson-Gomez   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

La “formación” del analista y sus avatares sintomáticos

open access: yesDesde el Jardín de Freud, 2010
Resumen La imposibilidad de formalización del acto analítico hace síntoma en las instituciones psicoanalíticas. El final relativo del análisis confronta al sujeto con aquello que podemos caracterizar como lo fundamental de su existencia, como el ...
Francisco Rengifo Lozano
doaj   +2 more sources

STATE OF PUBLIC BUILDINGS IN GHANA AFTER THE PASSAGE OF THE PERSONS WITH DISABILITY ACT (ACT 715): THE CASE OF TERTIARY INSTITUTIONS

open access: yesJournal of Construction Project Management and Innovation, 2012
Persons with disability Act (ACT 715) makes it mandatory to put up buildings that are disabled friendly but most designers and contractors in Ghana fail to factor the disabled people in the design and construction of infrastructure.
Samuel K. Ansah, Kwaku Owusu
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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