Results 81 to 90 of about 7,368,504 (211)

Sequence-Regulated Polymers via Combination of Orthogonal Passerini Three-Component Reaction and Thiol-ene Reaction

open access: yes, 2014
The present work describes a facile approach to sequence-regulated polymers via a combination of orthogonal Passerini three-component reaction and thiol-ene reaction.
Zi-Chen Li   +7 more
core   +1 more source

Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions

open access: yesBeilstein Journal of Organic Chemistry, 2019
Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the ...
Angélica de Fátima S. Barreto   +1 more
doaj   +1 more source

Biocompatible Unimolecular Micelles Obtained via the Passerini Reaction as Versatile Nanocarriers for Potential Medical Applications.

open access: yesBiomacromolecules, 2018
A Passerini three-component polymerization was performed for the synthesis of amphiphilic star-shaped block copolymers with hydrophobic cores and hydrophilic coronae.
S. Oelmann   +6 more
semanticscholar   +1 more source

Derivatization of Abietane Acids by Peptide-like Substituents Leads to Submicromolar Cytotoxicity at NCI-60 Panel

open access: yesMolecules
Natural compounds, including diterpenoids, play a critical role in various biological processes and are recognized as valuable components in cancer treatment.
Elena Tretyakova   +3 more
doaj   +1 more source

Green Multicomponent Reaction for the Organic Chemistry Laboratory. The Aqueous Passerini Reaction.

open access: yes, 2009
Water is the ideal green solvent for organic reactions. However, most organic molecules are insoluble in it. Herein, we report a laboratory module that takes advantage of this property.
DeBoef, Brenton, Hooper, Matthew M.
core   +1 more source

Total Synthesis of 4-epi-Bengamide E

open access: yesMolecules
Bengamide E is a bioactive natural product that was isolated from Jaspidae sponges by Crews and co-workers in 1989. It displays a wide range of biological activities, including antitumor, antibiotic, and anthelmintic properties.
Gabriella Vitali Forconesi   +8 more
doaj   +1 more source

Synthesis of Novel Indole Derivatives, Antiproliferative Activity, Apoptosis, and Molecular Docking Studies

open access: yesActa Chimica Slovenica
Novel indole-containing analogs were synthesized via a one-pot, multi-component Passerini reaction and subsequently evaluated for their anticancer activity against HeLa, MCF-7, and A549 cancer cell lines using the MTT assay.
Mahsa Toolabi   +3 more
doaj   +1 more source

REPARAÇÃO DE α-ACETILOXI-N-CICLOEXILAMIDAS ATRAVÉS DA REAÇÃO DE PASSERINI UTILIZANDO DIMETILCARBONATO COMO SOLVENTE AMBIENTALMENTE AMIGÁVEL

open access: yesQuímica Nova
A series of α-acetyloxy-N-cyclohexylamides was efficiently obtained via Passerini reaction of cyclohexyl isocyanide, acetic acid, and different aromatic and aliphatic aldehydes using refluxing dichloromethane or dimethylcarbonate (DMC).
Bárbara R. Oliveira   +5 more
doaj   +1 more source

Effect of Component Variation on the Passerini-Smiles Reaction

open access: yes, 2016
A multicomponent coupling reaction (MCR) is a powerful transformation, combining three or more starting materials to form several new bonds in a one-pot process that efficiently affords highly functionalized molecular scaffolds.
Summers, Chante
core  

Synthesis of Passerini−Ugi Hybrids by a Four-Component Reaction Using the Glycolaldehyde Dimer

open access: yes, 2016
Passerini−Ugi hybrid adducts can be obtained through a four-component reaction by using glycolaldehyde ...
Gian Cesare Tron (1520005)   +2 more
core   +1 more source

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