Immediate protection of an animal can be achieved by passive immunization—the administration of preformed antibodies to a susceptible animal. These antibodies have historically been produced in hyperimmunized horses.
I. Tizard
europepmc +7 more sources
Passive Immunization in Alpha-Synuclein Preclinical Animal Models [PDF]
Alpha-synucleinopathies include Parkinson’s disease, dementia with Lewy bodies, pure autonomic failure and multiple system atrophy. These are all progressive neurodegenerative diseases that are characterized by pathological misfolding and accumulation of
Jonas Folke +4 more
doaj +3 more sources
The role of passive immunization in the age of SARS-CoV-2: an update [PDF]
The rapid spread of the corona virus pandemic is an existential problem for many people in numerous countries. So far, there is no effective vaccine protection or proven therapy available against the SARS-CoV-2 virus. In this review, we describe the role
Johannes C. Fischer +19 more
doaj +3 more sources
Polyclonal hyper immunoglobulin: A proven treatment and prophylaxis platform for passive immunization to address existing and emerging diseases [PDF]
Passive immunization with polyclonal hyper immunoglobulin (HIG) therapy represents a proven strategy by transferring immunoglobulins to patients to confer immediate protection against a range of pathogens including infectious agents and toxins.
Tharmala Tharmalingam +3 more
doaj +3 more sources
Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques. [PDF]
The latent viral reservoir is the critical barrier for developing an HIV-1 cure. Previous studies have shown that therapeutic vaccination or broadly neutralizing antibody (bNAb) administration, together with a Toll-like receptor 7 (TLR7) agonist ...
Walker-Sperling VEK +19 more
europepmc +2 more sources
Passive immunization of the human vagina [PDF]
The vagina is an excellent site for topical passive immunization, as access is relatively easy, and it is an enclosed space that has been shown to retain bioactive antibodies for several hours.
Deborah J. Anderson
doaj +2 more sources
Antibodies to SARS-CoV-2 and Their Potential for Therapeutic Passive Immunization [PDF]
We review aspects of the antibody response to SARS-CoV-2, the causative agent of the COVID-19 pandemic. The topics we cover are relevant to immunotherapy with plasma from recovered patients, monoclonal antibodies against the viral S-protein, and soluble ...
Klasse P, Moore JP.
europepmc +3 more sources
Active and Passive Immunization with Myelin Basic Protein as a Method for Early Treatment of Traumatic Spinal Cord Injury; a Meta-Analysis [PDF]
Introduction: Traumatic spinal cord injury (SCI), as a dangerous central nervous system damage, continues to threaten communities by imposing various disabilities and costs.
Mahmoud Yousefifard +7 more
doaj +2 more sources
Cell-based passive immunization for protection against SARS-CoV-2 infection [PDF]
Background Immunologically impaired individuals respond poorly to vaccines, highlighting the need for additional strategies to protect these vulnerable populations from COVID-19.
Evan Sawula +9 more
doaj +2 more sources

