Results 101 to 110 of about 5,255,194 (298)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Creating change through leadership development:
Journal of the Canadian Health Libraries AssociationIn 2019, CHLA/ABSC launched the first Leadership Institute for health librarians in Canada. This article provides an overview of how the Leadership Institute (LI) was developed and delivered, the content and structure of the LI, lessons learned from ...
Miriam Ticoll, Sandy Iverson
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
On June 11, 2026, the German automotive company Volkswagen was convicted in four different lawsuits by the Brazilian Labor Court for reducing people to slavery in the Brazilian Amazon. While this judgment marks the company’s second round of convictions for enslavement within the Amazonian state of Pará, it stands out as a historic first in the form of ...
Matos, Saulo de, Guimarães, Heitor
openaire +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
, 2018 Le projet Papuan Past associe les approches archéologiques et génomiques afin d'étudier les modalités de peuplement et d’adaptation des populations – évolution biologiques, culturelles, et techniques – au cours des cinquante derniers millénaires en ...
editorsppp
core
Past-year khat and marijuana use across level of education.
Past-year khat and marijuana use across level of education.
John Ssenkusu (6715634) +5 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source