Results 101 to 110 of about 4,524,183 (368)
TEACHING SIMPLE PAST TENSE AND PRESENT PERFECT TENSE TO THE EIGHT GRADERS OF SMPN 22 SURAKARTA [PDF]
, 2011 This final project is written based on the job training which has been done in SMPN 22 Surakarta for eight weeks. The writer had an opportunity to teach English lesson for the eight graders and focused on teaching grammar.
Indriastuti, hanita
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Qualitative Social Research in Spain: Past, Present, and Future. A Portrait
Forum: Qualitative Social Research, 2005 Cartographic work has always gone hand in hand with the effort for the advancement of knowledge in many fields. In this paper we will sketch a cartography of qualitative methodology in Spain.
Miguel S. Valles, Alejandro Baer
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Polis, 2011 El artículo propone que México tiene pendiente la tarea de imaginar sus futuros de largo plazo, planteando que es urgente que lo haga en un esfuerzo colectivo, sistemático y riguroso.
Antonio Alonso Concheiro
doaj
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Anthropological Sense of History
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen'Purpose. The paper’s main purpose is to establish the nature of the historical past’s reality and its presence in being. Theoretical basis. The author considers historical time as a factor in the identities of individuals and society. The past has a dual
A. V. Halapsis
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source