Results 81 to 90 of about 4,524,183 (368)

Professor Yücel Tümer, MD; a legend, mentor in children’s orthopaedics in Turkey

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Hakan Ömeroğlu, Muharrem Yazıcı
doaj   +1 more source

Archaeological fieldwork at Eripe cave complex (Gulf province, Papua New Guinea)

open access: yes
From the 29th May to the 20th of June 2024, a team of six people carried out the 2nd fieldwork of the Papuan Past Project in the Purari region, following our 2023 survey.
Papuan Past Project Editors
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Quanto l’archeologia diventa un’opportunità per disegnare il futuro / How much archaeology becomes an opportunity to design the future

open access: yesIl Capitale Culturale: Studies on the Value of Cultural Heritage, 2019
Il paper presenta il modello dell’Area archeologica di Poggio del Molino a Populonia (Piombino, LI) attraverso l’intervento dell’Associazione culturale Past in Progress che ha, nel tempo, acquisito una grande rilevanza, soprattutto a livello ...
Stefano Monti, Carolina Megale
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Generating hope in pastoral care through relationships

open access: yesHTS Teologiese Studies/Theological Studies, 2012
This article concerned itself with the notion of Christian hope, in the midst of suffering, where this hope will find its energy from within a relationship with God and his people.
Tobias H. Steyn, Maake J. Masango
doaj   +1 more source

Understanding the climate of the past 2000 years: Phase 3of the PAGES 2k Network

open access: yes, 2017
The PAGES 2k Network was created with the aim of reconstructing changes in regional and global surface climate over the past 2000 years. During Phases 1 (2008-2013) and 2 (2014-2016), regional and trans-regional groupings focused on building ...
Phipps, Steven   +8 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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