Results 61 to 70 of about 5,255,194 (298)
The book under review is a study of manuscript texts from Warring States and early imperial China (approximately the 5th to 2nd centuries BCE); its specific topic is “manuscript collections,” that is, “single manuscripts containing multiple (originally)
Newell Ann Van Auken
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Critics have often described The Death of the Heart as a Bildungsroman centred on the character of Portia, in her progress towards maturity. If such a vision is undoubtedly valid, this article attempts to show that the novel can be better comprehended by
Céline Magot
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Taking the Potomac Cowbirdlike
Since her college years at Bryn Mawr, where she majored in both History and Politics, Marianne Moore was always extremely conscious of contemporary society and deeply immersed in history.
Paola A. Nardi
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Past bodies: Body-centered research in archaeology
Archaeology often struggles in envisioning real people behind the world of material objects it studies. Even when dealing with skeletal remains archaeologists routinely reduce them to long lists of figures and attributes.
core +4 more sources
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
This article is about the interpretation of national history in the context of universal history, which was begun by Karamzin and continued by Granovsky and Kliuchevskoi.
ZHUKOVA O.A. / ЖУКОВА О.А.
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

