Results 51 to 60 of about 1,385,162 (283)

Leadership in Academia: Dean’s Disease – Its Sources, Seductions, and Solutions [PDF]

open access: yes, 2016
This paper analyzes the behavioral dysfunction known colloquially as “dean’s disease” in terms of the classic group of mortal sins to which we are all susceptible and the particular problems faced when serving in an administrative capacity in academia ...
Cantrell, Pat
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Pengaruh Harga, Kualitas Pelayanan, dan Inovasi Desain Terhadap Loyalitas Pembelian Merk Minorfighters

open access: yesJKBM (Jurnal Konsep Bisnis dan Manajemen), 2019
The increasing growth of retail products in Indonesia has led to the increasing level of competition in the retail business faced by domestic products. The usefulness of this research is to detect the influence of price levels, service quality and design
Roymon Panjaitan
doaj   +1 more source

Establishment of an ELISA Method for Quantitative Detection of PAT/pat in GM Crops

open access: yesAgriculture, 2022
The phosphinothricin N-acetyltransferase gene (pat) is widely used to confer resistance to the herbicide phosphinothricin for genetically modified (GM) crops.
Weixiao Liu   +4 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Excitation of earthquakes by microseismic noise and weather phenomena

open access: yesГеофизический журнал, 2013
To describe the role of hydrological cycle dynamics in stimulation of weak earthquakes the conception of hydroseismicity is used; hydroseismicity is characterized by the influence of physical-chemical processes in the geological environment and the ...
P. V. Anakhov, M. V. Makarets
doaj   +1 more source

Association between periodontal disease and pericardial adipose tissue in patients with cardiovascular disease

open access: yesAmerican Heart Journal Plus, 2023
Background: Periodontal disease (PD) is associated with an increased risk of cardiovascular disease (CVD). Pericardial adipose tissue (PAT) is known as a marker of progressive CVD.
Yoshinori Kanno   +16 more
doaj   +1 more source

Documentary realism and fundamentalist religion in Ireland: a case study of power in the blood together with The Rocky Road to Dublin and The Road to God Knows Where [PDF]

open access: yes, 2009
Introduction: According to many critics documentary helps to interpret history and promote human understanding while dramatising and bending reality.
Brereton, Pat
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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