Results 41 to 50 of about 6,562 (141)
Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing
Journal of Electrical and Computer Engineering, 2011 Since raw data recorded by patch-clamp systems are always stored in binary format, electrophysiologists may experience difficulties with patch clamp data preprocessing especially when they want to analyze by custom-designed algorithms.
Ning Zhang +5 more
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The Touch and Zap method for in vivo whole-cell patch recording of intrinsic and visual responses of cortical neurons and glial cells. [PDF]
PLoS ONE, 2014 Whole-cell patch recording is an essential tool for quantitatively establishing the biophysics of brain function, particularly in vivo. This method is of particular interest for studying the functional roles of cortical glial cells in the intact brain ...
Adrien E Schramm +3 more
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Patch-walking, a coordinated multi-pipette patch clamp for efficiently finding synaptic connections
eLifeSignificant technical challenges exist when measuring synaptic connections between neurons in living brain tissue. The patch clamping technique, when used to probe for synaptic connections, is manually laborious and time-consuming.
Mighten C Yip +10 more
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Setting up a new gold standard: automated temperature-controlled hERG test on Patchliner®
Frontiers in Pharmacology, 2012 In the present study, the Patchliner® temperature-controlled automated patch clamp system was evaluated for testing actions of drugs on K+ currents through hERG channels expressed in CHO cells at 35-37°C.
Liudmila ePolonchuk
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Frontiers in Pharmacology, 2011 All excitable cell functions rely upon ion channels that are embedded in their plasma membrane. Perturbations of ion channel structure or function result in pathologies ranging from cardiac dysfunction to neurodegenerative disorders.
Christophe ePy +11 more
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Patch Clamp for MoS2 Layer‐Dependent Hydrogen Evolution Reaction
ChemElectroChemConventional electrochemical experiments can only obtain the average contribution of all active sites in the catalyst. Hence, it is meaningful to distinguish the electrochemical contribution of the local active sites in single‐crystal catalysts.
Zhipeng Zhang +10 more
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Reducing agents facilitate membrane patch seal integrity and longevity
ChannelsThe patch clamp method is a widely applied electrophysiological technique used to understand ion channel activity and cellular excitation. The formation of a high resistance giga-ohm seal is required to obtain high-quality recordings but can be ...
Damayantee Das +5 more
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Patch clamp study of benzydamine effect over neuronal excitability on inflammation sensitized rat nociceptors [PDF]
, 2023 Antonio Ferrer‐Montiel +7 more
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Distinct degree of radiculopathy at different levels of peripheral nerve injury
Molecular Pain, 2012 Background Lumbar radiculopathy is a common clinical problem, characterized by dorsal root ganglion (DRG) injury and neural hyperactivity causing intense pain. However, the mechanisms involved in DRG injury have not been fully elucidated.
Takiguchi Noboru +7 more
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