Results 141 to 150 of about 5,720,247 (293)

Microfluidic device for cell screening and patch-clamp analysis

, 2012
The purpose is to realize a Lab-On-Chip based device for cell screening and electrophysiological assay to introduce the Patch-Clamp as a routine clinical test.
Valbusa U, Firpo G, Repetto L, Guida P
core   +1 more source

Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices

Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices. This project aims to characterise the interaction of transport proteins with unsupported lipid bilayer membranes. This will provide the basis

core  

Temperature‐Modulated MEMS Gas Sensor Array Enabled by Physics‐Informed Deep Learning for Thermal‐Runaway Characteristic Gas Discrimination

Advanced Science, EarlyView.
This work presents a 2 × 2 integrated single‐chip MEMS gas sensor array with temperature modulation and deep learning for discriminating thermal‐runaway characteristic gases. The array generates distinct temperature‐modulated response patterns for four characteristic gases (H2, CO, CH4, and CO2), while a HK‐MoE model is developed to achieve robust ...
Qin Luo, Qi Guo, Rongyue Liu, Yilin Li, Haiping Zhu, Wei Zhang, Zhongren Chen, Zhaojun Liu, Xing Cheng   +8 more
wiley   +1 more source

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Matlab software for analyzing patch-clamp recordings (viewEPSC)

<p>Matlab code for analyzing electrophysiology data obtained via whole-cell  patch-clamp recordings.</p ...
Broeke, Jurjen, Huson, Vincent
core   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

Durability of a novel mechanical aortic valve closure technique during left ventricular assist device support: A comparative case report. [PDF]

JHLT Open
Shiozaki Y, Ichihara Y, Yoshizawa S, Saito S, Niinami H.   +4 more
europepmc   +1 more source

Recording light-evoked postsynaptic responses in neurons in dark-adapted, mouse retinal slice preparations using patch clamp techniques. [PDF]

J Vis Exp, 2015
Hellmer CB, Ichinose T.
europepmc   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Dielectrophoresis and ζ-potential as potential low-cost complements to patch clamp for measurement of cell electrophysiology. [PDF]

PLoS One
Hoque R, Labeed FH, Cirovic S, Hughes MP.   +3 more
europepmc   +1 more source