Results 141 to 150 of about 39,769 (255)

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

Deep patch-clamp recordings in awake mice from medial septal neurons during hippocampal sharp-wave ripples. [PDF]

Neuroreport
Samejima H, Sato Y, Ikegaya Y, Kashima T.   +3 more
europepmc   +1 more source

Anomalous Enhancement in MXene‐Based Electrochemical Actuators: Pseudo‐Capacitance‐Induced Multi‐Charge Accumulation in Confined Space

Advanced Science, EarlyView.
We elucidate the electrochemical actuation mechanism of 2D material‐based electrodes within a MXene‐centered framework, linking atomic‐scale surface chemistry to macroscopic performance (see schematic). Mechanistically, the reduction of Ti─O─Ti sites in H2SO4 triggers the accumulation of hydrated ions at confined active sites, resulting in anomalous ...
Jiang Xu, Jipeng Feng, Bingqing Hu, Xude Li, Shifei Huang, Shanhai Ge, Guoxiu Wang   +6 more
wiley   +1 more source

Combined patch-clamp electrophysiology and single-cell genomic analysis reveal spiking tumor cells at the neocortical glioblastoma interface in humans. [PDF]

Neuro Oncol
Tong T, Hendriksen JD, Elbæk KJ, Molnar K, Christiansen FV, Ozsvar A, Eschen JT, Rodríguez-González FG, Pusat ID, Christensen EL, Rahbæk M, Frederiksen KP, Cortnum SOS, Sindby AK, Meier K, Nikola, Sørensen JCH, Ting JT, Capogna M, Kristensen BW, Nyengaard JR, Weischenfeldt J, Hou WH, Korshøj AR.   +23 more
europepmc   +1 more source

From Sourcing to End‐of‐Life: Sustainability Challenges and Opportunities in Organic Bioelectronics

Advanced Science, EarlyView.
Organic bioelectronics bridges biology and electronics using organic mixed ionic/electronic conductors. This Perspective addresses sustainability across the full lifecycle of organic bioelectronic materials and devices, offering a framework to guide material sourcing, synthesis, fabrication, application, and end‐of‐life strategies toward bioelectronic ...
Gwennaël Dufil, Marine Batista, Andrea Bionda, Erica Zeglio   +3 more
wiley   +1 more source

Severe mitral regurgitation after aortic annular enlargement with Y-incision: a case report. [PDF]

J Cardiothorac Surg
Özçelik S, Gojayev F.
europepmc   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

Short- and Mid-Term Outcomes of Bovine Pericardial Patch vs. Saphenous Vein Patch in Femoral Endarterectomy. [PDF]

Ann Vasc Dis
Harada T, Futagami D, Echie Y, Watanabe S, Morimoto H, Katayama K, Mukai S, Taniguchi M.   +7 more
europepmc   +1 more source

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source

Perfusion strategy and surgical repair of Type A interrupted aortic arch and Type 1 aortopulmonary window: a case report. [PDF]

J Extra Corpor Technol
Leigh P, Harman E, Husain SA.
europepmc   +1 more source