Results 71 to 80 of about 741,076 (339)

Unstructured spline spaces for isogeometric analysis based on spline manifolds

, 2015
Based on spline manifolds we introduce and study a mathematical framework for analysis-suitable unstructured B-spline spaces. In this setting the parameter domain has a manifold structure, which allows for the definition of function spaces that have a ...
Sangalli, Giancarlo, Takacs, Thomas, Vázquez, Rafael   +2 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Isogeometric B\'ezier dual mortaring: Refineable higher-order spline dual bases and weakly continuous geometry

, 2017
In this paper we develop the isogeometric B\'ezier dual mortar method. It is based on B\'ezier extraction and projection and is applicable to any spline space which can be represented in B\'ezier form (i.e., NURBS, T-splines, LR-splines, etc.).
Borden, M. J., Brivadis, E., Dornisch, W., Scott, M. A., Thomas, D. C., Zou, Z.   +5 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

A parallel multigrid solver for multi-patch Isogeometric Analysis

, 2018
Isogeometric Analysis (IgA) is a framework for setting up spline-based discretizations of partial differential equations, which has been introduced around a decade ago and has gained much attention since then.
C Douglas, C Hofreither, C Hofreither, G Sangalli, LB Veiga da, LB Veiga da, M Donatelli, N Collier, S Takacs, SK Kleiss, TJR Hughes   +10 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Experimental Study on Influence of Different Patterns of an Emergent Vegetation Patch on the Flow Field and Scour/Deposition Processes in the Wake Region

Water Resources Research
Flume experiments were conducted to comprehend the impact of different patterns of an emergent vegetation patch on the flow field and the scour process in natural rivers.
Oral Yagci, V. S. Özgur Kirca, Vasileios Kitsikoudis, Catherine A. M. E. Wilson, M. Furkan Celik, Caner Sertkan   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Efficacy of 13.3 mg/24 h versus 4.6 mg/24 h rivastigmine patch on activities of daily living in severe Alzheimer’s disease

SAGE Open Medicine, 2014
Objective: Investigate efficacy of 13.3 mg/24 h rivastigmine patch in patients with severe Alzheimer’s disease on Alzheimer’s Disease Cooperative Study–Activities of Daily Living Scale–Severe Impairment Version items and domains.
Joseph L Micca, James E Galvin, Drew M Velting, Xiangyi Meng   +3 more
doaj   +1 more source

Cantilever Plate Mid-Span Patch Method for Dynamically Testing the In-Plane Poisson's Ratio of Oriented Strand Board

BioResources, 2023
A cantilever plate span-to-span patch method was proposed and demonstrated for dynamic testing of OSB Poisson's ratio with high testing accuracy, simplicity, ease of implementation, and effectiveness.
Yuying Zou, Zheng Wang, Yifan Zhang, Yuhao Zhou, Zhaoyu Shen   +4 more
doaj   +2 more sources