Results 91 to 100 of about 326,151 (193)

Distinct degree of radiculopathy at different levels of peripheral nerve injury

open access: yesMolecular Pain, 2012
Background Lumbar radiculopathy is a common clinical problem, characterized by dorsal root ganglion (DRG) injury and neural hyperactivity causing intense pain. However, the mechanisms involved in DRG injury have not been fully elucidated.
Takiguchi Noboru   +7 more
doaj   +1 more source

Modern tendencies in the development of the patch-clamp technique: new opportunities for neuropharmacology and neurobiology

open access: yesАнналы клинической и экспериментальной неврологии, 2017
The patch-clamp (PC) technique is the gold standard in studyingprocesses that occur on the membranes of excitable cells,both in the physiological condition and in pathology.
A. N. Shuvaev   +4 more
doaj   +1 more source

NOVEL TECHNIQUES FOR IN VIVO CHARACTERIZATION OF SHORT PEPTIDES AND PROTEINS IN MEMBRANE PERMEABILIZATION AND SIGNAL TRANSDUCTION [PDF]

open access: yes, 2012
My scientific interest is focused on the field of cellular electrical activity, ranging from the study of intracellular enzymatic processes to the characterization of new generation of drugs.
Aquila, Marco
core  

Planar patch clamp for neuronal networks - Considerations and future perspectives

open access: yes, 2014
The patch-clamp technique is generally accepted as the gold standard for studying ion channel activity allowing investigators to either "clamp" membrane voltage and directly measure transmembrane currents through ion channels, or to passively monitor ...
Bosca, Alessandro   +5 more
core   +1 more source

Clamp Tie and Surgery Bucket Module: How to Build

open access: yes, 2018
"Clamp and Tie Module Goal: residents should be able to pass a silk tie atraumatically around a clamped structure and tie into a hole. Clamp and Tie Module Instructions: (Can be completed solo or with partner): 1.
Peter Bartline MD; Ruth Braga MSN; William Peche MD; Daniel Vargo MD
core  

Clamp Tie and Surgery Bucket Module: Surgical Bucket Ingredient List

open access: yes, 2018
"Clamp and Tie Module Goal: residents should be able to pass a silk tie atraumatically around a clamped structure and tie into a hole. Clamp and Tie Module Instructions: (Can be completed solo or with partner): 1.
Peter Bartline MD; Ruth Braga MSN; William Peche MD; Daniel Vargo MD
core  

The activation thresholds and inactivation kinetics of poking-evoked PIEZO1 and PIEZO2 currents are sensitive to subtle variations in mechanical stimulation parameters

open access: yesChannels
PIEZO1 and PIEZO2 are mechanically activated ion channels that confer mechanosensitivity to various cell types. PIEZO channels are commonly examined using the so-called poking technique, where currents are recorded in the whole-cell configuration of the ...
Nadja Zeitzschel, Stefan G. Lechner
doaj   +1 more source

Clamp Tie and Surgery Bucket Module: Figure of 8 Compiled Pics

open access: yes, 2018
"Clamp and Tie Module Goal: residents should be able to pass a silk tie atraumatically around a clamped structure and tie into a hole. Clamp and Tie Module Instructions: (Can be completed solo or with partner): 1.
Peter Bartline MD; Ruth Braga MSN; William Peche MD; Daniel Vargo MD
core  

Microfluidic polymeric device for improved planar patch-clamp

open access: yes, 2012
Ion channels are under-exploited membrane protein target class, due to the labour-intensive and low-throughput nature of traditional patch-clamp. Basic and clinical research require much efficiency, higher throughput and procedures simplification ...
Valbusa U, Firpo G, Repetto L, Guida P
core   +1 more source

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