Results 81 to 90 of about 152,269 (192)

Lipid Ion Channels

, 2010
The interpretation electrical phenomena in biomembranes is usually based on the assumption that the experimentally found discrete ion conduction events are due to a particular class of proteins called ion channels while the lipid membrane is considered ...
Heimburg, Thomas
core   +1 more source

Distinct degree of radiculopathy at different levels of peripheral nerve injury

Molecular Pain, 2012
Background Lumbar radiculopathy is a common clinical problem, characterized by dorsal root ganglion (DRG) injury and neural hyperactivity causing intense pain. However, the mechanisms involved in DRG injury have not been fully elucidated.
Takiguchi Noboru, Yoshida Munehito, Taniguchi Wataru, Hashizume Hiroshi, Yamada Hiroshi, Miyazaki Nobuyuki, Nishio Naoko, Nakatsuka Terumasa   +7 more
doaj   +1 more source

Modern tendencies in the development of the patch-clamp technique: new opportunities for neuropharmacology and neurobiology

Анналы клинической и экспериментальной неврологии, 2017
The patch-clamp (PC) technique is the gold standard in studyingprocesses that occur on the membranes of excitable cells,both in the physiological condition and in pathology.
A. N. Shuvaev, V. V. Salmin, N. V. Kuvacheva, E. A. Pozhilenkova, A. B. Salmina   +4 more
doaj   +1 more source

Patch-Clamp Study of Hepatitis C p7 Channels Reveals Genotype-Specific Sensitivity to Inhibitors [PDF]

, 2016
Ulrike Breitinger, Noha S. Farag, Nourhan K. M. Ali, Hans-Georg A. Breitinger   +3 more
openalex   +1 more source

Electrophysiological evaluation of the effect of peptide toxins on voltage-gated ion channels: a scoping review on theoretical and methodological aspects with focus on the Central and South American experience [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases
The effect of peptide toxins on voltage-gated ion channels can be reliably assessed using electrophysiological assays, such as the patch-clamp technique.
Jessica Rojas-Palomino, Alejandro Gómez-Restrepo, Cristian Salinas-Restrepo, César Segura, Marco A. Giraldo, Juan C. Calderón   +5 more
doaj   +1 more source

Detecting and Estimating Signals in Noisy Cable Structures, I: Neuronal Noise Sources [PDF]

, 1999
In recent theoretical approaches addressing the problem of neural coding, tools from statistical estimation and information theory have been applied to quantify the ability of neurons to transmit information through their spike outputs. These techniques,
Koch, Christof, Manwani, Amit
core   +1 more source

An offline correction method for uncompensated series resistance and capacitance artifacts from whole-cell patch clamp recordings of small cells [PDF]

, 2011
Cengiz Günay, Astrid A. Prinz
openalex   +1 more source

[3/3] Patch clamp of a Purkinje cell in a simulated cerebellar cortex model during single impulse stimulation

, 2022
Robin De Schepper
openalex   +2 more sources

Modulation of Ca ²⁺ Signaling by Microtubule Disruption in Rat Ventricular Myocytes and Its Dependence on the Ruptured Patch-Clamp Configuration [PDF]

, 2001
Sarah Calaghan, J.-Y. Le Guennec, Ed White   +2 more
openalex   +1 more source

The activation thresholds and inactivation kinetics of poking-evoked PIEZO1 and PIEZO2 currents are sensitive to subtle variations in mechanical stimulation parameters

Channels
PIEZO1 and PIEZO2 are mechanically activated ion channels that confer mechanosensitivity to various cell types. PIEZO channels are commonly examined using the so-called poking technique, where currents are recorded in the whole-cell configuration of the ...
Nadja Zeitzschel, Stefan G. Lechner
doaj   +1 more source