Results 81 to 90 of about 752,311 (360)
Whole-cell Patch-clamp Recordings in Brain Slices.
Journal of Visualized Experiments, 2016 Whole-cell patch-clamp recording is an electrophysiological technique that allows the study of the electrical properties of a substantial part of the neuron.
Amir Segev, F. Garcia-Oscos, S. Kourrich
semanticscholar +1 more source
Toughness of Confined Auxetic Foams
Advanced Engineering Materials, EarlyView.Auxetic (negative Poisson's ratio) materials offer benefits such as impact mitigation, thermal insulation, vibration damping, and reduced shear strain, although their fracture mechanics are largely unexplored. This study investigates damage initiation and propagation in confined re‐entrant auxetic foams from polyurethane via experimental ...
Adrianos E. F. Athanasiadis +3 more
wiley +1 more source
Nanotechnology: new opportunities for the development of patch‐clamps
Journal of Nanobiotechnology, 2021 The patch-clamp technique is one of the best approaches to investigate neural excitability. Impressive improvements towards the automation of the patch-clamp technique have been made, but obvious limitations and hurdles still exist, such as ...
Jia Gao +4 more
doaj +1 more source
The Circadian Clock Gene Period1 Connects the Molecular Clock to Neural Activity in the Suprachiasmatic Nucleus. [PDF]
, 2015 The neural activity patterns of suprachiasmatic nucleus (SCN) neurons are dynamically regulated throughout the circadian cycle with highest levels of spontaneous action potentials during the day.
Block, Gene D +2 more
core +1 more source
Automated Patch Clamp Meets High-Throughput Screening
Journal of laboratory automation, 2016 We have developed an automated patch clamp module for high-throughput ion channel screening, recording from 384 cells simultaneously. The module is incorporated into a laboratory pipetting robot and uses a 384-channel pipettor head for application of ...
Alison Obergrussberger +15 more
semanticscholar +1 more source
Advanced Engineering Materials, EarlyView.This study presents a multimodal characterization method for a prototype metamaterial model structure that features four distinct states of mechanical stiffness and electrical resistivity. Through simulations and experiments, it uncovers insights into the structural behavior, the correlation between changes in electrical resistivity and mechanical ...
Rebecca Kose +3 more
wiley +1 more source
Single-channel recordings from cultured human retinal pigment epithelial cells. [PDF]
, 1988 We have applied patch-clamp techniques to on-cell and excised-membrane patches from human retinal pigment epithelial cells in tissue culture. Single-channel currents from at least four ion channel types were observed: three or more potassium-selective ...
Fain, GL, Fox, JA, Pfeffer, BA
core
Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF [PDF]
, 2016 STUDY QUESTION. Are significant abnormalities in outward (K+) conductance and resting membrane potential (Vm) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success?
Barratt, Christopher L. R. +9 more
core +6 more sources
Journal of Visualized Experiments, 2017 Over the past decade, channelrhodopsins became indispensable in neuroscientific research where they are used as tools to non-invasively manipulate electrical processes in target cells.
C. Grimm +3 more
semanticscholar +1 more source
The patch-clamp technique in the study of secretion [PDF]
Trends in Neurosciences, 1989 One of the basic cellular functions of virtually every cell type is the exocytotic release of molecules synthesized, stored and packaged into intracellular vesicles or granules. Over decades much effort has been concentrated on elucidating the chain of events leading to exocytosis.
Penner, Reinhold, Neher, Erwin
openaire +3 more sources