Results 61 to 70 of about 191,816 (321)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Recover Fine-Grained Spatial Data from Coarse Aggregation

, 2017
In this paper, we study a new type of spatial sparse recovery problem, that is to infer the fine-grained spatial distribution of certain density data in a region only based on the aggregate observations recorded for each of its subregions.
Kong, Linglong, Liu, Bang, Mavrin, Borislav, Niu, Di   +3 more
core   +1 more source

S-patch: Modification of the Hermite parametric patch

, 2022
A new modification of the Hermite cubic rectangular patch is proposed: the S-Patch, which is based on the requirement that diagonal curves must be of degree 3 instead of degree 6 as it is in the case of the Hermite patch. Theoretical derivation of conditions is presented and some experimental results as well. The S-Patch is convenient for applications,
Skala, Vaclav, Ondracka, Vit
openaire   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Classification of Sleep Apnea Severity by Electrocardiogram Monitoring Using a Novel Wearable Device

Sensors, 2020
Sleep apnea (SA) is a prevalent disorder diagnosed by polysomnography (PSG) based on the number of apnea−hypopnea events per hour of sleep (apnea−hypopnea index, AHI).
Florent Baty, Maximilian Boesch, Sandra Widmer, Simon Annaheim, Piero Fontana, Martin Camenzind, René M. Rossi, Otto D. Schoch, Martin H. Brutsche   +8 more
doaj   +1 more source

Marginal Fermi Liquid with a Two-Dimensional Patched Fermi Surface

, 1999
We consider a model composed of Landau quasiparticle states with patched Fermi surfaces (FS) sandwiched by states with flat FS to simulate the ``cold'' spot regions in cuprates. We calculate the one particle irreducible function and the self-energy up to
A. FERRAZ, T. SAIKAWA, Z. Y. WENG, Zheleznyak A. T.   +3 more
core   +1 more source

Con-Patch: When a Patch Meets Its Context [PDF]

IEEE Transactions on Image Processing, 2016
Measuring the similarity between patches in images is a fundamental building block in various tasks. Naturally, the patch-size has a major impact on the matching quality, and on the consequent application performance. Under the assumption that our patch database is sufficiently sampled, using large patches (e.g. 21-by-21) should be preferred over small
Yaniv Romano, Michael Elad
openaire   +4 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Counterfeit Detection of Iranian Black Tea Using Image Processing and Deep Learning Based on Patched and Unpatched Images

Horticulturae
Tea is central to the culture and economy of the Middle East countries, especially in Iran. At some levels of society, it has become one of the main food items consumed by households.
Mohammad Sadegh Besharati, Raziyeh Pourdarbani, Sajad Sabzi, Dorrin Sotoudeh, Mohammadreza Ahmaditeshnizi, Ginés García-Mateos   +5 more
doaj   +1 more source