Results 51 to 60 of about 4,974 (149)

Gas Chromatography–Mass Spectroscopy (GC–MS) Simultaneous Determination of Limonene, Linalool, and Linalyl Acetate in Rat Plasma Following Transdermal Administration of the Essential Oil of Bergamot Loaded Onto Solid Lipid Nanoparticles (NanoBEO)

Phytotherapy Research, Volume 40, Issue 2, Page 488-492, February 2026.
Luigi A. Morrone, Laura Rombolà, Antonella Leggio, Emilia L. Belsito, Ludovica Scorzafave, Enrica De Rasis, Martina Pagliaro, Kengo Hamamura, Takafumi Hayashi, Giacinto Bagetta, Maria Tiziana Corasaniti, Damiana Scuteri   +11 more
wiley   +1 more source

Impact of Alzheimer's disease on sleep in adults with Down syndrome

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION Down syndrome (DS) is a genetic form of Alzheimer's disease (AD), with a high prevalence of sleep disorders, but data in adults with DS and dementia are lacking. We aim to assess sleep in adults with DS across the AD continuum. METHODS We studied 78 healthy controls and 229 adults with DS (154 asymptomatic, 25 with prodromal AD ...
Sandra Giménez, Lídia Vaqué‐Alcázar, Nuole Zhu, Bessy Benejam, Javier Arranz, Lucia Maure‐Blesa, Laura Videla, Maria Carmona‐Iragui, Isabel Barroeta, Anne‐Sophie Rebillat, Íñigo Rodríguez‐Baz, Alexandre Bejanin, José Enrique Arriola‐Infante, Ana Bueno, Susana Fernandez, Laia Ribas, Sara E. Zsadanyi, Alejandra O. Morcillo‐Nieto, Daniel Alcolea, Christos Panagiotis Lisgaras, Esther Blessing, Ricardo S. Osorio, Alberto Lleó, Juan Fortea   +23 more
wiley   +1 more source

Nanopartículas lipídicas: aplicações cosméticas [PDF]

, 2013
Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasTendo em conta a sua composição e as vantagens que apresentam, as nanopartículas lipídicas ...
Silva, Diana Patrícia Pinto da
core  

Reflexiones sobre las nuevas directivas de patentabilidad para invenciones farmacéuticas

Revista Iberoamericana de la Propiedad Intelectual, 2013
Lo que se pretende es realizar un ejercicio de reflexión sobre la aplicación del sistema de patentes al ámbito de los medicamentos farmacéuticos tomando como tópico disparador la Resolución Conjunta citada.
Pablo Tomás Lamas
doaj  

Diagnostic performance of plasma Aβ42/40 ratio, p‐tau181, GFAP, and NfL along the continuum of Alzheimer's disease and non‐AD dementias: An international multi‐center study

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract INTRODUCTION Plasma phosphorylated tau (p‐tau)181, glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), and amyloid beta ratio (Aβ42/40) may have diagnostic and prognostic value in Alzheimer's disease (AD). Here we assess which markers can best identify AD from controls and other non‐AD dementias in a large international ...
James D. Doecke, Giovanni Bellomo, Lisa Vermunt, Daniel Alcolea, Steffen Halbgebauer, Sjors in ’t Veld, Niklas Mattsson‐Carlgren, Katerina Veverova, Christopher J. Fowler, Lynn Boonkamp, Isabel M. Houtkamp, Marleen Koel‐Simmerlink, Inge M. W. Verberk, Lorenzo Gaetani, Andrea Toja, Anna Lidia Wojdała, Juan Fortea, Yolande Pijnenburg, Afina Lemstra, Wiesje van der Flier, Jakub Hort, Markus Otto, Oskar Hansson, Lucilla Parnetti, Colin L. Masters, Alberto Lleó, Armand González‐Escalante, José Contador, Marc Suárez‐Calvet, Aida Fernández‐Lebrero, Albert Puig‐Pijoan, Paula Ortiz‐Romero, Esther Jiménez‐Moyano, Carolina Minguillón, Marta del Campo, Charlotte Teunissen   +35 more
wiley   +1 more source

Propriedade intelectual e saúde pública: a cópia de medicamentos contra HIV/Aids realizada por laboratórios farmacêuticos brasileiros públicos e privados

RECIIS, 2007
A experiência dos laboratórios brasileiros públicos e privados em copiar ARVs (anti-retrovirais), desde 1993, constitui um processo de aprendizado tecnológico que, em alguns casos, produziu inovações.
Maurice Cassier, Marilena Correa
doaj   +1 more source

Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract INTRODUCTION Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders.
Mathias Sauer, Bárbara Fernandes Gomes, Parasto Shahrouki, Juan Lantero‐Rodriguez, Laia Montoliu‐Gaya, Elena Camporesi, Olivia Belbin, Daniel Alcolea, Ashish Kumar, Mitu Sharma, Sangeeta Singh, Gunnar Brinkmalm, Johan Gobom, María Carmona‐Iragui, Michael Schöll, Shorena Janelidze, Gagan Deep, Kaj Blennow, Henrik Zetterberg, Ann Brinkmalm, Alberto Lleó, Juan Fortea, Oskar Hansson, Nicholas J. Ashton, Johanna Nilsson   +24 more
wiley   +1 more source

Patentes Farmacêuticas e direito à saúde

Scientia Iuris, 2011
O presente trabalho tem por objetivo a análise do instituto das patentes de segundo uso médico, não expressamente regulamentado na ordem jurídica brasileira.  Nesta tarefa, valer-se-á do marco teórico da Teoria do Direito como Integridade.
Gustavo Candian Filardi, Marcos Vinício Chein Feres   +1 more
doaj  

The Down Alzheimer Barcelona Neuroimaging Initiative (DABNI) and its contributions to understanding Alzheimer's disease in Down syndrome: A decade of discovery

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract Down syndrome (DS) is a genetic form of Alzheimer's disease (AD) that offers crucial insights into AD pathogenesis. The Down Alzheimer Barcelona Neuroimaging Initiative (DABNI) is a population‐based multimodal biomarker cohort studying AD's natural history and clinical trials in DS.
Laura Videla, Bessy Benejam, Isabel Barroeta, Susana Fernandez, Miren Altuna, Javier Arranz, Íñigo Rodríguez‐Baz, José Enrique Arriola‐Infante, Lucía Maure‐Blesa, Laura del Hoyo Soriano, Ignacio Illán‐Gala, Teresa Estellés, Aida Sanjuan, Lídia Vaqué‐Alcázar, Mateus Rozalem Aranha, Alejandra O. Morcillo‐Nieto, Sarah Erzsebet Zsadanyi, Maria Franquesa‐Mullerat, Sílvia Valldeneu, María Belén Sánchez‐Saudinós, Concepción Padilla, Mireia Carreras, Oriol Lorente, Natalia Valle‐Tamayo, Érika Sánchez‐Aced, Oriol Dols‐Icardo, Sònia Sirisi, Laia Muñoz, Soraya Torres, Shaima El Bounasr El Bennadi, Oriol Sánchez, Diana Garzón, Laia Ribas, Sumia Elbachiri, Cecilia Mota, Mireia Tondo, Valle Camacho, Sandra Giménez, Constance Delaby, Olivia Belbin, María Florencia Iulita, Víctor Montal, Jordi Pegueroles, Eduard Vilaplana, Jordi Clarimón, Sofía González‐Ortiz, Laura Molina‐Porcel, Iban Aldecoa, Daniel Alcolea, Alexandre Bejanin, Sebastià Videla, Rafael Blesa, Alberto Lleó, María Carmona‐Iragui, Juan Fortea   +54 more
wiley   +1 more source

La financiarización de las grandes empresas farmacéuticas

Revista Internacional de Sociología, 2020
En este artículo, empleamos un marco Vebleniano para analizar tres dimensiones de la financiarización corporativa: la expansión del balance, la creciente importancia de los activos intangibles y los crecientes niveles de pagos financieros.
Tobias J. Klinge, Rodrigo Fernandez, Manuel B. Aalbers   +2 more
doaj   +1 more source