Results 31 to 40 of about 6,101,409 (287)

An observational analysis of the impact of indoor residual spraying with non-pyrethroid insecticides on the incidence of malaria in Ségou Region, Mali: 2012–2015

open access: yesMalaria Journal, 2018
Background Ségou Region in Central Mali is an area of high malaria burden with seasonal transmission, high access to and use of long-lasting insecticidal nets (LLINs), and resistance to pyrethroids and DDT well documented in Anopheles gambiae s.l.
Joseph Wagman   +14 more
doaj   +1 more source

Onsager-Machlup action-based path sampling and its combination with replica exchange for diffusive and multiple pathways

open access: yes, 2010
For sampling multiple pathways in a rugged energy landscape, we propose a novel action-based path sampling method using the Onsager-Machlup action functional.
Akinori Kidera   +3 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

DMPA-SC self-injection experiences of clients and providers in Uganda: the role of community health workers in reproductive self-care service delivery

open access: yesBMC Women's Health
Accelerating task sharing for family planning and contraceptive self-care can minimize the impact of a projected shortage of 18 million health care workers by 2030.
Jane Cover   +5 more
doaj   +1 more source

Path [PDF]

open access: yes, 2018
Path is a collaborative system that developed over the course of five months of studio activity and continued through the duration of the exhibition. The system’s main collaborators were a land snail native to eastern North America (Neohelix albolabris),
Galbicka, Evan
core   +1 more source

Corrections to the Boltzmann mean free path in disordered systems with finite size scatterers

open access: yes, 2001
The mean free path is an essential characteristic length in disordered systems. In microscopic calculations, it is usually approximated by the classical value of the elastic mean free path.
Correia S   +10 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Directed path graphs [PDF]

open access: yes, 1996
The concept of a line digraph is generalized to that of a directed path graph. The directed path graph $\overrightarrow P_k(D)$ of a digraph D is obtained by representing the directed paths on k vertices of D by vertices.
Broersma, Hajo, Li, Xueliang
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Comparative analysis of the use of Community Health Workers while deploying the Attractive Targeted Sugar Bait (ATSB) for malaria control in Western Province, Zambia

open access: yesMalaria Journal
Background Community Health Workers (CHWs) play a crucial role in malaria control efforts, yet their contributions to large-scale field trials remain understudied.
Frank Ndalama   +14 more
doaj   +1 more source

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