Results 51 to 60 of about 2,070,985 (262)
Clinical and Translational Science, 2021 Interest in drug development for rare diseases has expanded dramatically since the Orphan Drug Act was passed in 1983, with 40% of new drug approvals in 2019 targeting orphan indications. However, limited quantitative understanding of natural history and
Ariana P. Mullin +10 more
doaj +1 more source
Raj Path should have been renamed Dharma Path [PDF]
, 2022 The freshly inaugurated Central Vista indeed will bring laurels to the country. Like the Avenue des Champs-Élysées in Paris that passes through the Arc de Triomph, the Kartavya Path too passes through the India Gate but the entire vista is much more ...
Batra, Jagdish
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Augmented Speed Enforcement Project at PATH: Minimizing Hazards in Work Zones in Rural Areas [PDF]
, 2013 The Partners for Advanced Transportation Technology (PATH) developed, implemented, and field-tested an Augmented Speed Enforcement (aSE) system that will help enforce reduced speed limits in construction zones and thereby protect personnel working in the
California PATH
core +1 more source
Smarandachely t-path step signed graphs [PDF]
, 2010 Characterizing signed graphs which are switching equivalent to their Smarandachely 3-path step signed ...
Reddy, Siva Kota +5 more
core +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
BMJ Global HealthReaching the Sustainable Development Goal 2030 global mortality and morbidity targets will require increased access to essential health services. Scaling high-impact health interventions within the public sector is complex; delineation of the pathway to ...
Jessica C Shearer +12 more
doaj +1 more source
Progress report on the PATH Through Life Study [PDF]
, 2000 We finished interviewing people in their 20s in March this year, by which time we had interviewed 2404 people. Analysis of the 20-plus data is well under way. Our research team is currently preparing articles for scientific journals.
PATH Through Life Project
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source