Results 71 to 80 of about 4,045,344 (304)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Elimination of Branch, Grashof, and Order Defects in Path-Angle Generation and Function Generation Synthesis

open access: yes, 1979
Path-Angle Generation and Function Generation synthesis problems are restated as Plane-Position (or Motion Generation) problems, enabling the use of the classical Burmester technique and recent extensions that permit the avoidance of Branch, Grashof, and
K. J. Waldron, E. N. Stevensen
core   +1 more source

Improving Walking Path Generation Through Biped Constraint in Indoor Navigation System for Visually Impaired Individuals

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
This paper introduces a walking path generation method specifically developed for the Smart Cane, which is a RNA (Robotic Navigation Assistance Device) aimed at enhancing indoor navigation for visually impaired individuals. The proposed approach combines
Qingquan Na   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Development of Location-Data-Based Orchard Passage Map Generation Method

open access: yesSensors
Currently, pest control work using speed sprayers results in increasing numbers of safety accidents such as worker pesticide poisoning and rollover of vehicles during work.
Joong-hee Han   +2 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Research on algorithm of optimized sub-regional scanning path generation for RPM

open access: yes, 2007
Rapid prototyping is a technology of layered manufacturing; therefore, the scanning path of certain layer is quite important. An algorithm of sub-regional scanning path generation is presented in the paper.
Xia RB(夏仁波)   +3 more
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Efficient tool path generation for root 3 subdivision surface

open access: yes, 2006
An approach of three-axis NC cutter path generation for root 3 subdivision surface is proposed. A computing formula for error estimating root 3 subdivision surface is derived. Using the formula, one can predict how many steps of subdivision are necessary
Wu JH(吴剑煌)   +2 more
core  

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