The regulatory mechanism of NLRP3 inflammasome in the "immune paralytic-overactivation" imbalance in sepsis: the latest progress from molecular signaling to clinical translation. [PDF]
Zhou G +4 more
europepmc +1 more source
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma +10 more
wiley +1 more source
Gut-derived bacterial extracellular vesicles: the microbial dark matter contributing to host inflammation and cardiometabolic disease. [PDF]
Oliver B +6 more
europepmc +1 more source
From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley +1 more source
Deciphering the mechanistic involvement of PANoptosis in FC-MDD comorbidity through the gut-brain axis. [PDF]
Ma Y, Wang S, Wei W, Cheng C.
europepmc +1 more source
Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal +3 more
wiley +1 more source
Quadratic Concentration-Response Modeling and Molecular Docking of <i>Mespilodaphne quixos</i> (Lam.) Rohwer Essential Oil Against <i>Candida albicans</i>. [PDF]
Arteaga-Crespo Y +7 more
europepmc +1 more source
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang +10 more
wiley +1 more source
Biostimulation of Tomato Plants (<i>Solanum lycopersicum</i> L.) Using Fragmented Extracellular DNA from <i>Clavibacter michiganensis</i>. [PDF]
Carbajal-Valenzuela IA +4 more
europepmc +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source

