Many but not all pathogen-associated molecular patterns aggravate neurogenic heterotopic ossification after spinal cord injury. [PDF]
Samuel SG +12 more
europepmc +1 more source
The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li +4 more
wiley +1 more source
Innovative strategies for high-throughput discovery and engineering of plant immune receptors. [PDF]
Zhao W, Sun T, Zhang Y, Fu ZQ, Que Y.
europepmc +1 more source
Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm +9 more
wiley +1 more source
Molecular Mechanisms of Mucormycosis Pathogenesis: Host-Pathogen Interactions and Immune Evasion. [PDF]
Alanazi A +3 more
europepmc +1 more source
Volunteers stayed 3 h indoors and followed 1 h outdoors in a flowering meadow. Nasal mycobiome was analysed and aeroallergen content measured in nasal filters. Airborne fungal spores were quantified and fungal isolates were sequenced. Isolated fungal spores were used for stimulation of nasal epithelial cells.
Annika Eggestein +15 more
wiley +1 more source
Pathogenicity and virulence of the blast fungus <i>Magnaporthe oryzae</i>. [PDF]
Molinari C, Talbot NJ.
europepmc +1 more source
Beta‐Glucan: A Macrophage Differentiation Modulator That Accelerates the Wound Healing Response
ABSTRACT Beta Glucans (β‐glucans) are naturally occurring polysaccharides that have positive effects on healing in acute and chronic wounds. This study aimed to identify how β‐glucans modulate macrophage polarisation and inflammation to aid the healing response.
Stuart James Mills +4 more
wiley +1 more source
The F-box Containing Bacterial Effector RipG6 Destabilizes a Receptor-Like Cytoplasmic Kinase Involved in Plant Immune Signaling. [PDF]
Jeon H +4 more
europepmc +1 more source
The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley +1 more source

