The TG2/LRP1 Pathway for T Cell Activation by Post‐Translationally Modified Antigens
ABSTRACT Post‐translational modifications (PTMs) can generate neo‐epitopes, modified peptides that evade immune tolerance and trigger immune responses. This review focuses on the TG2/LRP1 pathway as a new paradigm for coupling the formation of post‐translationally modified peptides with their effective presentation as T‐cell antigens by dendritic cells.
Agnele Sylvia Sewa +2 more
wiley +1 more source
Functional Analysis Identifies Multiple Effectors of Candidatus Liberibacter Asiaticus Suppressing Plant Pattern-Triggered Immunity. [PDF]
He Z +7 more
europepmc +1 more source
Bacterial pathogens colonise woody hosts by integrating metabolic adaptation, effector‐mediated immune suppression, cell wall remodelling and EPS‐ and toxin‐supported persistence. ABSTRACT Bacterial pathogens of woody plants represent a pervasive yet underexplored threat to global agriculture and forestry, causing devastating diseases in fruit trees ...
Antonio Arroyo‐Mateo +3 more
wiley +1 more source
Innovative strategies for high-throughput discovery and engineering of plant immune receptors. [PDF]
Zhao W, Sun T, Zhang Y, Fu ZQ, Que Y.
europepmc +1 more source
Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar +4 more
wiley +1 more source
Biofilm-Host Immune Crosstalk at the Diabetic Foot Ulcer Interface: Molecular Mechanisms, Immune Evasion, and Next-Generation Anti-Biofilm Strategies. [PDF]
Han Y, Yang Y.
europepmc +1 more source
Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng +8 more
wiley +1 more source
Learning from plants: is it possible to make an animal organism a non-host for cancer? [PDF]
Nemchinov LG.
europepmc +1 more source
ABSTRACT Biotic stresses, particularly Verticillium wilt (VW), lead to a global decline in cotton yields. Here, we demonstrate that ectopic expression of ScALDH21, a gene from the desiccation‐tolerant moss Syntrichia caninervis Mitt. and absent in angiosperms, enhances cotton's resistance to VW.
Honglan Yang +13 more
wiley +1 more source
Research Progress of Peach Bacterial Spot Disease. [PDF]
Lu W, Du W, Chen C.
europepmc +1 more source

