Results 101 to 110 of about 3,211,185 (261)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A first genome assembly of the barley fungal pathogen Pyrenophora teres f. teres [PDF]

, 2011
Background: Pyrenophora teres f. teres is a necrotrophic fungal pathogen and the cause of one of barley's most important diseases, net form of net blotch.
Ellwood, S.R., Syme, R.A., Liu, Z.H., Friesen, T.L., Moffat, C.S., Oliver, R.P., Keiper, F., Lai, Z.B., Hane, J.K.   +8 more
core  

Integrating metagenomic next-generation sequencing into a multimodal diagnostic framework for spinal infection: enhancing etiological identification and clinical prediction

Frontiers in Cellular and Infection Microbiology
BackgroundSpinal infection (SI) remains diagnostically challenging because of heterogeneous etiologies, nonspecific clinical manifestations, and the limited sensitivity of conventional microbiological approaches, particularly following empirical ...
Heng Liang, Hongyuan Qin, Jiayi Chen, Chengyu Qin, Xulin Li, Qiaojun Wang, Guoming Luo, Yuanming Chen   +7 more
doaj   +1 more source

Real time PCR quantification of Sclerotium rolfsii in chilli tissue and soil

Plant Protection Science, 2015
Root rot disease caused by Sclerotium rolfsii is one of the important factors limiting chilli production in southern China. Rapid methods of detection and identification of S. rolfsii are required for disease prediction and management. Herein, we adapted
Yu-Han GAO, Wu MIAO, Rong-Jun GUO, Shi-Dong LI   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Identification and Antimicrobial Susceptibility Testing Performance for Short Incubation of Gram-Negative Pathogens from Bloodstream Infections at a Tertiary Care Center in Telangana

Journal of Pharmacy and Bioallied Sciences
Background and Objectives: Blood culture is the “gold standard” for diagnosing bacteremia. This study evaluates the performance of shortened incubation cultures in pathogen identification (ID) and antimicrobial susceptibility testing (AST) using the ...
Neelima Sudharshan, Sayeeda Munawar, MVNL Ram Mohan, SD Fatima Tasneem, C Padmasri, P Umabala, C Sudharshan Raj   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Broad range molecular detection methods identify only Borrelia spp. in erythema migrans biopsies and blood of tick-bitten patients

One Health
In this multicenter study conducted in France, we challenged the hypothesis of the transmission of pathogens other than Borrelia spp. in 22 patients developing erythema migrans following a tick bite.
Philippe Pérot, Laura Tondeur, Sara Moutailler, Delphine Chrétien, Nicole Corre-Catelin, Muriel Vayssier-Taussat, Marc Eloit, Catherine Chirouze, Céline Cazorla, Laurence Arowas, Elisabeth Botelho-Nevers, Céline Cazorla, Catherine Chirouze, Delphine Chrétien, Nicole Corre-Catelin, Marc Eloit, Pascale Frey-Klett, Arnaud Fontanet, Clémence Galon, Karine Lacombe, Sara Moutailler, Philippe Pérot, Véronique Perronne, Valentine Piquard, Marie Préau, Costanza Puppo, Laura Tondeur, Marie-Noelle Ungeheuer, Muriel Vayssier-Taussat, Ayla Zayoud   +29 more
doaj   +1 more source

Identification of pathogens causing fruit spot disease on Citrus grandis

浙江大学学报. 农业与生命科学版, 2018
Recently, a fruit spot disease was found on pummelo [Citrus grandis Osbeck, Syn. C. maxima (Burm) Merr.] fruits during our investigation of diseases in pummelo orchards as well as in packing houses in Guangdong, Guangxi, and Fujian provinces and ...
LÜ Jingwen, LIU Rui, LI Guohua, LI Hongye, WANG Hongkai   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source