Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Phosphorylation and proteome dynamics in pathogen-resistant tomato plants [PDF]
Microbial plant pathogens impose a continuous threat on global food production. Similar to disease resistance in mammals, an innate immune system allows plants to recognise pathogens and swiftly activate defence.
Stulemeijer, I.J.E.
core
Indian jujube (Ziziphus mauritiana) is an economically important crop in Thailand. During 2024–2025, anthracnose and rot symptoms were observed on postharvest Indian jujube fruits in northern Thailand. Thus, this study aimed to identify the causal agents
Wipornpan Nuangmek +8 more
doaj +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Identification results of clinical pathogen strains.
Identification results of clinical pathogen strains.
Guanwu Chen (523351) +6 more
core +1 more source
Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction [PDF]
BACKGROUND: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection.
Panda, G. +32 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The Identification, Isolation and Partial Characterisation of VapA-encoding virulence plasmids in Rhodococcus equi found in New Zealand. [PDF]
This thesis describes the identification, isolation and partial characterisation of VapA-encoded virulence plasmids present in Rhodococcus equi (R. equi) found in foals in New Zealand. R.
Singh, Niharika
core
Deep proteogenomics; high throughput gene validation by multidimensional liquid chromatography and mass spectrometry of proteins from the fungal wheat pathogen Stagonospora nodorum [PDF]
Background Stagonospora nodorum, a fungal ascomycete in the class dothideomycetes, is a damaging pathogen of wheat. It is a model for necrotrophic fungi that cause necrotic symptoms via the interaction of multiple effector proteins with cultivar ...
Hane, J. +24 more
core +1 more source
Background: Vascular graft infections (VGI) are difficult to diagnose and treat, and despite redo surgery combined with antimicrobial treatment, outcomes are often poor.
Evelyne Ajdler-Schaeffler +20 more
doaj +1 more source

