Results 71 to 80 of about 3,211,185 (261)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Genome structure and pathogenicity of the fungal wheat pathogen Mycosphaerella graminicola [PDF]

, 2011
The phytopathogenic fungus Mycosphaerella graminicola (Fuckel) J. Schröt. in Cohn (asexual stage: Zymoseptoria tritici (Desm.) Quaedvlieg & Crous) causes septoria tritici leaf blotch (STB) in wheat and is one of the most important diseases of this crop ...
Ben M'Barek, S., M'Barek, S., Ben
core  

The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay [PDF]

, 2008
This work was partly supported by grants from The Research Council of Norway and the University of Tromsø.Background: The fish pathogen Aliivibrio salmonicida is the causative agent of cold-water vibriosis in marine aquaculture.
Parkhill Julian, Paulsen, Steinar, Thomson Nicholas R, Lorentzen, Marit Sjo, Sanders, Suzanne, Quail, Michael A., Norbertczak, Halina, Thurston, Scott, Erik Hjerde, Holden, Matthew TG, Hjerde Erik, Suzanne Sanders, Holden, Matthew T. G., Sanders Suzanne, Julian Parkhill, Seeger, Kathy, Lorentzen Marit, Norbertczak Halina, Bason Nathalie, Thurston Scott, Quail Michael A, David Harris, Paulsen Steinar, Michael A Quail, Quail, Michael A, Matthew TG Holden, Steinar Paulsen, Hjerde, Erik, Parkhill, Julian, Harris David, Seeger Kathy, Kathy Seeger, Scott Thurston, Nathalie Bason, Holden Matthew TG, Carol Churcher, Willassen, Nils Peder, Bason, Nathalie, Churcher, Carol, Marit Lorentzen, Halina Norbertczak, Thomson, Nicholas R, Thomson, Nicholas R., Nils Willassen, Harris, David, Nicholas R Thomson, Churcher Carol, Willassen Nils   +47 more
core   +3 more sources

Identification of Bletilla striata rust pathogen and resistance resources screening

Guangxi Zhiwu
In order to identify the pathogen that caused rust of Bletilla striata in Guangxi Zhuang Autonomous Region and to screen resistance resources for B. striata, the rust pathogen was isolated from infected leaves of B.
WU Qiaofen, MA Xiaoya, XIA Ke, LU Xi, LIU Qiao, ZHAO Zhiguo, ZHENG Wenjun, QIU Shuo   +7 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Identification of receptor complex components and receptor activation mechanisms in plant innate immunity [PDF]

, 2011
Plants rely on an innate immune system which successfully recognizes and restricts pathogenic microbes. The key for this defense is the detection of pathogen derived non-self signatures and endogenous elicitors released during a microbial attack.
Mentzel, Tobias
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Balancing Selection at the Tomato RCR3 Guardee Gene Family Maintains Variation in Strength of Pathogen Defense [PDF]

, 2012
Coevolution between hosts and pathogens is thought to occur between interacting molecules of both species. This results in the maintenance of genetic diversity at pathogen antigens (or so-called effectors) and host resistance genes such as the major ...
Anja C. Hörger, Rose, Laura E., Renier A. L. Van Der, Renier A. L. van der Hoorn (150148), Van Der Hoorn, RAL, van der Hoorn, RA, Hoerger, A., Rose, LE, Van der Hoorn, R., Muhammad Ilyas, Laura E Rose, Ilyas, M, Laura E. Rose (150153), Hörger, Anja C., Laura E. Rose, Hoerger, AC, Rose, L., Aurélien Tellier, Van Der Hoorn, Renier, Stephan, Wolfgang, Hörger, AC, Tellier, A, Tellier, A., Muhammad Ilyas (150134), Anja C Hörger, van der Hoorn, Renier A. L., Anja C. Hörger (150127), Tellier, Aurélien, Stephan, W., Wolfgang Stephan (14960), Aurélien Tellier (150142), Renier A L van der Hoorn, Wolfgang Stephan, Stephan, W, Ilyas, M., Ilyas, Muhammad, van der Hoorn Renier A. L., Rose Laura E., Tellier Aurélien, Stephan Wolfgang, Hörger, Anja C.;Ilyas, Muhammad;Stephan, Wolfgang;Tellier, Aurélien;van der Hoorn, Renier A. L.;Rose, Laura E., Ilyas Muhammad, Hörger Anja C.   +42 more
core   +2 more sources

Identification the Pathogen Cause a New Apple Leaf Blight in China and Determination the Controlling Efficacy for Five Botanical Fungicides

Journal of Fungi
Alternaria leaf blight has recently been described as an emerging fungal disease of apple trees which is causing the significant damage in the apple-growing areas of Tianshui and Jingning, Gansu, China. In the present study, the pathogen species involved
Enchen Li, Jia Liu, Shuwu Zhang, Bingliang Xu   +3 more
doaj   +1 more source