Results 101 to 110 of about 1,694,622 (312)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
Pathogenesis of Alzheimer′s disease
, 2007 Russell H SwerdlowDepartment of Neurology, University of Virginia School of Medicine, Charlottesville, VA, USAAbstract: Alzheimer’s disease (AD) is incredibly common. Increasing longevity ensures its prevalence will rise even further.
Russell H Swerdlow
core
, 2018 Protein acetylation and deacetylation play vital roles in the structural and physiological behavior of target proteins. Histone deacetylase 6 (HDAC6) remains a key therapeutic target in several chronic diseases such as cancer, neurodegenerative, and ...
Shailima Rampogu (3856018) +5 more
core +1 more source
Candida glabrata: A Lot More Than Meets the Eye
Microorganisms, 2019 Candida glabrata is an opportunistic human fungal pathogen that causes superficial mucosal and life-threatening bloodstream infections in individuals with a compromised immune system. Evolutionarily, it is closer to the non-pathogenic yeast Saccharomyces
Kundan Kumar +3 more
doaj +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
The pathogenesis-related proteins of tobacco leaves
, 1986 Extracts from the leaves of tobacco plants (cv. Xanthi-nc.) which are reacting hypersensitively to infection with TMV contain the four well-known pathogenesis-related proteins (PR-Ia, b, c and II), and in addition other PR-proteins which can be ...
Pierpoint, W. S.
core +1 more source
Clinical Validation of Plasma p‐217tau in Neurological Diseases
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
Blood viscosity at different stages of diabetes pathogenesis
, 2010 Hyperglycaemia-induced oxidative stress is implicated as a cause of increased whole blood viscosity (WBV), which is a clinically modifiable risk factor for cardiovascular disease (CVD).
Richards, R. S., Nwose, E. U.
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, 2018 Over 250 species of resident flora in the class of bacteria are known to be associated with humans. These conventional flora compositions is often determined by factors which may not be limited to genetics, age, sex, stress and nutrition of humans.
Ugbogu, Eziuche Amadike +6 more
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