Results 11 to 20 of about 1,837,939 (209)

Pathogenesis-adaptive polydopamine nanosystem for sequential therapy of ischemic stroke

open access: yes, 2023
This is a dataset of the manuscript entitled "Pathogenesis-adaptive polydopamine nanosystem for sequential therapy of ischemic stroke"
Jing Zhou (17072139)   +10 more
core   +4 more sources

TSE pathogenesis in cattle and sheep [PDF]

open access: yes, 2008
Many studies have been undertaken in rodents to study the pathogenesis of transmissible spongiform encephalopathies (TSE). Only a few studies have focused on the pathogenesis of bovine spongiform encephalopathy (BSE) and scrapie in their natural hosts ...
Bossers, A.   +10 more
core   +1 more source

The pathogenesis of Acanthamoeba infections: current status and future implications [PDF]

open access: yes, 2004
Acanthamoeba are opportunistic protozoan parasites that can cause painful, visionthreatening keratitis. However the pathogenesis and pathophysiology of Acanthamoeba keratitis remain incompletely understood. Most cases of Acanthamoeba keratitis develop
Khan, Naveed Ahmed
core   +5 more sources

Yap governs a lineage-specific neuregulin1 pathway-driven adaptive resistance to RAF kinase inhibitors

open access: yesMolecular Cancer, 2022
Background Inactivation of the Hippo pathway promotes Yap nuclear translocation, enabling execution of a transcriptional program that induces tissue growth.
Maria E. R. Garcia-Rendueles   +10 more
doaj   +1 more source

4-Phenylbutyrate (PBA) treatment reduces hyperglycemia and islet amyloid in a mouse model of type 2 diabetes and obesity

open access: yesScientific Reports, 2021
Amyloid deposits in pancreatic islets, mainly formed by human islet amyloid polypeptide (hIAPP) aggregation, have been associated with loss of β-cell mass and function, and are a pathological hallmark of type 2 diabetes (T2D).
Sara de Pablo   +9 more
doaj   +1 more source

Alternate subunit assembly diversifies the function of a bacterial toxin

open access: yesNature Communications, 2019
Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory ...
Casey C. Fowler   +4 more
doaj   +1 more source

Pmp Repertoires Influence the Different Infectious Potential of Avian and Mammalian Chlamydia psittaci Strains

open access: yesFrontiers in Microbiology, 2021
Chlamydia psittaci is the etiological agent of chlamydiosis in birds and can be transmitted to humans, causing severe systemic disease. C. psittaci infects a broad range of hosts; strains are isolated not only from birds but also from mammals, where they
Alison Favaroni   +4 more
doaj   +1 more source

Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy

open access: yesnpj Vaccines, 2023
Staphylococcus aureus infections are a major public health issue, and a vaccine is urgently needed. Despite a considerable promise in preclinical models, all vaccines tested thus far have failed to protect humans against S. aureus. Unlike laboratory mice,
Omid Teymournejad   +4 more
doaj   +1 more source

The pathogenesis of dengue. [PDF]

open access: yes, 2011
Dengue is an important cause of childhood and adult morbidity in Asian and Latin American countries and its geographic footprint is growing. The clinical manifestations of dengue are the expression of a constellation of host and viral factors, some ...
Whitehorn, J   +6 more
core   +1 more source

Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. [PDF]

open access: yes, 2009
Cerebral malaria is a life-threatening complication of malaria infection. The pathogenesis of cerebral malaria is poorly defined and progress in understanding the condition is severely hampered by the inability to study in detail, ante-mortem, the ...
KEVIN N. COUPER   +11 more
core   +1 more source

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