Results 31 to 40 of about 1,837,939 (209)

Pathogenesis of Atherosclerosis

Journal of the American College of Cardiology, 2006
Atherosclerosis is a multifocal, smoldering, immunoinflammatory disease of medium-sized and large arteries fuelled by lipids. Endothelial cells, leukocytes, and intimal smooth muscle cells are the major players in the development of this disease. The most devastating consequences of atherosclerosis, such as heart attack and stroke, are caused by ...
openaire   +3 more sources

Pathogenesis of Behcet Syndrome

, 2014
Contribution of a chapter for the book "Behcet's Syndrome: From Pathogenesis to Treatment", Series Rare Diseases of the Immune System, edited by ...
Emmi L, Squatrito D, Emmi G, Silvestri E, Grassi A   +4 more
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A case report of multiple primary prostate tumors with differential drug sensitivity

Nature Communications, 2020
Prostate cancer is often a multifocal disease but how best to manage this clinically remains unclear. Here, the authors report a single case study of a patient with two genetically diverse tumours which showed differential response to therapy.
Scott Wilkinson, Stephanie A. Harmon, Nicholas T. Terrigino, Fatima Karzai, Peter A. Pinto, Ravi A. Madan, David J. VanderWeele, Ross Lake, Rayann Atway, John R. Bright, Nicole V. Carrabba, Shana Y. Trostel, Rosina T. Lis, Guinevere Chun, James L. Gulley, Maria J. Merino, Peter L. Choyke, Huihui Ye, William L. Dahut, Baris Turkbey, Adam G. Sowalsky   +20 more
doaj   +1 more source

Pathogenesis of endocrine thyroid cancer [PDF]

, 2015
This review aims to discuss the different genetic alterations that may come about and thus give rise to thyroid cancer. The importance of understanding the pathogenesis of this disease is in the use of these genetic alterations as prognostic markers and ...
Vassallo, Josanne, Mallia, Nicola
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Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma

Microorganisms, 2020
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto, Mattia Russel Pantalone, Afsar Rahbar, Cecilia Söderberg-Nauclér   +3 more
doaj   +1 more source

De Novo Isolation & Affinity Maturation of yeast-displayed Virion-binding human fibronectin domains by flow cytometric screening against Virions

Journal of Biological Engineering, 2019
Background The promise of biopharmaceuticals comprising one or more binding domains motivates the development of novel methods for de novo isolation and affinity maturation of virion-binding domains.
Pete Heinzelman, Alyssa Low, Rudo Simeon, Gus A. Wright, Zhilei Chen   +4 more
doaj   +1 more source

Control of CD4+ T cells to restrain inflammatory diseases via eukaryotic elongation factor 2 kinase

Signal Transduction and Targeted Therapy, 2023
CD4+ T cells, particularly IL-17-secreting helper CD4+ T cells, play a central role in the inflammatory processes underlying autoimmune disorders. Eukaryotic Elongation Factor 2 Kinase (eEF2K) is pivotal in CD8+ T cells and has important implications in ...
Hao-Yun Peng, Liqing Wang, Jugal Kishore Das, Anil Kumar, Darby J. Ballard, Yijie Ren, Xiaofang Xiong, Paul de Figueiredo, Jin-Ming Yang, Jianxun Song   +9 more
doaj   +1 more source

Pathogenesis and treatment of atopic dermatitis

, 2020
This thesis reviews the various pathways and molecular entities involved in the development and progression of Atopic Dermatitis. It dismantles the core components that are implicated in the pathogenesis of this disease.
Qasim, Hafsa
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Replication, Pathogenesis and Transmission of Pandemic (H1N1) 2009 Virus in Non-Immune Pigs [PDF]

, 2010
The declaration of the human influenza A pandemic (H1N1) 2009 (H1N1/09) raised important questions, including origin and host range [1,2]. Two of the three pandemics in the last century resulted in the spread of virus to pigs (H1N1, 1918; H3N2, 1968 ...
Essen, Stephen C., Bhudipa Choudhury, Jill Banks, Reeth, Kristien Van, Nunez, Alejandor, Garcon, Fanny, Nunez, A., Gardner, Rebecca, Van Reeth, Kristien, Bethany Nash, Brookes, Sharon M., Peter M H Heegaard, Alejandro Núñez, Foni, Emanuela, Irvine, Richard M., Foni, E., Jaime Maldonado Garcia, Stéphane Quéguiner, Emanuela Foni, Essen, Stephen C, Chiapponi, C., Larsen, Lars, Ian H Brown, Queguiner, S., Sharon M Brookes, Bublot, Michel, Slomka, M.J., Chiapponi, Chiara, Clifford, Derek, Garcia, Jaime M, Willie Loeffen, Choudhury, B., Nunez, Alejandro, Choudhury, Bhudipa, Kuntz-Simon, Gaélle, Essen, S.C., Matrosovich, M., Heegaard, P.M.H., Michel Bublot, Gardner, R., Matrosovich, Mikhail, Brookes, Sharon M, Brown, Ian H., Heegaard, Peter M. H., Fanny Garcon, Slomka, Marek J, Loeffen, Willie, Larsen, Lars Erik, Garcon, F., Loeffen, W.L.A., Heegaard, Peter MH, Irvine, R.M., Reeth, K., Banks, J., Chiara Chiapponi, Irvine, Richard M, Queguiner, Stéphane, Lars Larsen, Amanda Hanna, Kuntz-Simon, G., Brown, I.H., Banks, Jill, Richard M Irvine, Slomka, Marek J., Nash, Bethany, Garcia, Jaime Maldonado, Marek J Slomka, Nash, B., Mikhail Matrosovich, Hanna, Amanda, Stephen C Essen, Gaëlle Kuntz-Simon, Kristien Van Reeth, Derek Clifford, Rebecca Gardner, Hanna, A., Garcia, J.M., Brookes, S.M., Clifford, D., Brown, Ian H, Bublot, M., Heegaard, Peter M.H., Larsen, L.   +82 more
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Preeclampsia Pathogenesis

, 2020
Preeclampsia is usually defined as new-onset hypertension and proteinuria diagnosed at 20th gestational week or after. Preeclampsia is one of the leading causes of maternal and infant mortality worldwide.
Colcimen, N.
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