Results 41 to 50 of about 1,837,939 (209)
Seronegative spondyloarthropathies : a review : part II: genetics and pathogenesis [PDF]
, 1993 In none of the spondyloarthropathies is the pathogenesis well understood. Much of the investigation into the aetio-pathogenesis of these diseases has focused on the association with HLA-B27 and the known triggering potential of certain infectious agents.
Borg, Andrew A. +2 more
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Structural Insights into De Novo Promoter Escape by Mycobacterium tuberculosis RNA Polymerase
Nature CommunicationsTranscription in bacteria is a multi-step process. In the first step, contacts between RNA polymerase and the promoter DNA must be established for transcription initiation to begin, but then these contacts must be broken for the enzyme to transition into
Joshua Brewer +4 more
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Viruses, 2015 Human immunodeficiency virus type 1 (HIV-1) encodes four accessory genes: vif, vpu, vpr, and nef. Recent investigations using in vitro cell culture systems have shed light on the roles of these HIV-1 accessory proteins, Vif, Vpr, Vpu, and Nef, in ...
Eri Yamada +5 more
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Epigenetic Regulation of Antifungal Drug Resistance
Journal of Fungi, 2022 In medical mycology, epigenetic mechanisms are emerging as key regulators of multiple aspects of fungal biology ranging from development, phenotypic and morphological plasticity to antifungal drug resistance.
Sandip Patra +3 more
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Pathogenesis of pruritus [PDF]
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2011 SummaryThe pathogenesis of acute and chronic (> 6 weeks duration) pruritus is complex and involves in the skin a network of resident cells (e. g., mast cells, keratinocytes, sensory neurons) and transient inflammatory cells (e. g., eosinophils). Though pruritus and pain show overlapping mechanisms, recent studies have provided evidence that pruritus
Sonja, Ständer +6 more
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A Review of Literature Data in the Pathogenesis of Acne Vulgaris
, 2020 Acne Vulgaris is a prevalent skin disease worldwide. The disease occurs due to a variety of endogenous and exogenous factors which contribute to its pathogenesis.
Patel, Mirej
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The Pathogenesis of Autism [PDF]
Clinical medicine. Pathology, 2008 Autism is well known as a complex developmental disorder with a seemingly confusing and uncertain pathogenesis. The definitive mechanisms that promote autism are poorly understood and mostly unknown, yet available theories do appear to focus on the disruption of normal cerebral development and its subsequent implications on the functional brain unit ...
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MHC Class II Tetramer Labeling of Human Primary CD4+ T Cells from HIV Infected Patients
Bio-Protocol, 2017 Major Histocompatibility Complex (MHC) tetramers have been used for two decades to detect, isolate and characterize T cells specific for various pathogens and tumor antigens.
Moran Galperin +4 more
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The pathogenesis of NIDDM [PDF]
Diabetologia, 1994 Improvements in the specificity and sensitivity of assays for insulin-related molecules in the circulation have proved to be necessary and informative in studies of the pathogenesis of non-insulin-dependent diabetes (NIDDM). Of particular interest has been the close relationship between increases in des 31,32 split proinsulin and susceptibility to loss
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Novel Components of the Flagellar System in Epsilonproteobacteria
mBio, 2014 Motility is essential for the pathogenesis of many bacterial species. Most bacteria move using flagella, which are multiprotein filaments that rotate propelled by a cell wall-anchored motor using chemical energy. Although some components of the flagellar
Beile Gao +4 more
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