Results 21 to 30 of about 1,701,047 (213)

Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy

open access: yesnpj Vaccines, 2023
Staphylococcus aureus infections are a major public health issue, and a vaccine is urgently needed. Despite a considerable promise in preclinical models, all vaccines tested thus far have failed to protect humans against S. aureus. Unlike laboratory mice,
Omid Teymournejad   +4 more
doaj   +1 more source

Pmp Repertoires Influence the Different Infectious Potential of Avian and Mammalian Chlamydia psittaci Strains

open access: yesFrontiers in Microbiology, 2021
Chlamydia psittaci is the etiological agent of chlamydiosis in birds and can be transmitted to humans, causing severe systemic disease. C. psittaci infects a broad range of hosts; strains are isolated not only from birds but also from mammals, where they
Alison Favaroni   +4 more
doaj   +1 more source

Pathogenesis and treatment of atopic dermatitis [PDF]

open access: yes, 2020
This thesis reviews the various pathways and molecular entities involved in the development and progression of Atopic Dermatitis. It dismantles the core components that are implicated in the pathogenesis of this disease.
Qasim, Hafsa
core  

A Review of Literature Data in the Pathogenesis of Acne Vulgaris [PDF]

open access: yes, 2020
Acne Vulgaris is a prevalent skin disease worldwide. The disease occurs due to a variety of endogenous and exogenous factors which contribute to its pathogenesis.
Patel, Mirej
core  

The pathogenesis of dengue. [PDF]

open access: yes, 2011
Dengue is an important cause of childhood and adult morbidity in Asian and Latin American countries and its geographic footprint is growing. The clinical manifestations of dengue are the expression of a constellation of host and viral factors, some ...
Whitehorn, J   +6 more
core   +1 more source

Pathogenesis of pruritus [PDF]

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2011
SummaryThe pathogenesis of acute and chronic (> 6 weeks duration) pruritus is complex and involves in the skin a network of resident cells (e. g., mast cells, keratinocytes, sensory neurons) and transient inflammatory cells (e. g., eosinophils). Though pruritus and pain show overlapping mechanisms, recent studies have provided evidence that pruritus
Sonja, Ständer   +6 more
openaire   +2 more sources

Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. [PDF]

open access: yes, 2009
Cerebral malaria is a life-threatening complication of malaria infection. The pathogenesis of cerebral malaria is poorly defined and progress in understanding the condition is severely hampered by the inability to study in detail, ante-mortem, the ...
KEVIN N. COUPER   +11 more
core   +1 more source

Defining the therapeutic selective dependencies for distinct subtypes of PI3K pathway-altered prostate cancers

open access: yesNature Communications, 2021
Understanding the mechanisms driving PI3K isoform dependency in prostate cancer can help the design of future clinical trials. Here, the authors show that gain-of-function mutations in PIK3CA or PIK3CB can confer PI3K p110 isoform dependency and that the
Ninghui Mao   +17 more
doaj   +1 more source

Pathogenesis of chronic obstructive pulmonary disease [PDF]

open access: yes, 2005
The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
core   +1 more source

Escherichia coli resistant to the highest priority critically important fluoroquinolone or 3rd and 4th generation cephalosporin antibiotics persist in pigsties

open access: yesApplied and Environmental Microbiology
Antimicrobial resistance threatens human and animal health, with antimicrobial usage being a key driver of selection, transmission, and spread of resistant bacteria.
Nicola M. Pfeifer   +5 more
doaj   +1 more source

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