Results 21 to 30 of about 1,884,876 (261)

Nontypeable Haemophilus influenzae released from biofilm residence by monoclonal antibody directed against a biofilm matrix component display a vulnerable phenotype

open access: yesScientific Reports, 2023
Bacterial biofilms contribute significantly to pathogenesis, recurrence and/or chronicity of the majority of bacterial diseases due to their notable recalcitrance to clearance.
Kathryn Q. Wilbanks   +5 more
doaj   +1 more source

Yap governs a lineage-specific neuregulin1 pathway-driven adaptive resistance to RAF kinase inhibitors

open access: yesMolecular Cancer, 2022
Background Inactivation of the Hippo pathway promotes Yap nuclear translocation, enabling execution of a transcriptional program that induces tissue growth.
Maria E. R. Garcia-Rendueles   +10 more
doaj   +1 more source

Bacterial Pathogenesis : Methods and Protocols

open access: yes, 2023
This detailed volume presents a diverse set of methodological approaches designed to improve our understanding of bacterial infections from a wide range of bacterial species.
Collin, Mattias   +4 more
core   +1 more source

Pathogenesis of oral FIV infection [PDF]

open access: yes, 2017
Feline Immunodeficiency Virus; FIV Pathogenesis; Saliva; oral; transmission; Oral Transmission; HIV; HIV-Induced Oral Disease; HIV pathogenesis.Feline immunodeficiency virus (FIV) is the feline analogue of human immunodeficiency virus (HIV) and features ...
Miller, Craig A.
core   +3 more sources

The pathogenesis of dengue. [PDF]

open access: yes, 2011
Dengue is an important cause of childhood and adult morbidity in Asian and Latin American countries and its geographic footprint is growing. The clinical manifestations of dengue are the expression of a constellation of host and viral factors, some ...
Whitehorn, J   +5 more
core   +1 more source

Alternate subunit assembly diversifies the function of a bacterial toxin

open access: yesNature Communications, 2019
Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory ...
Casey C. Fowler   +4 more
doaj   +1 more source

4-Phenylbutyrate (PBA) treatment reduces hyperglycemia and islet amyloid in a mouse model of type 2 diabetes and obesity

open access: yesScientific Reports, 2021
Amyloid deposits in pancreatic islets, mainly formed by human islet amyloid polypeptide (hIAPP) aggregation, have been associated with loss of β-cell mass and function, and are a pathological hallmark of type 2 diabetes (T2D).
Sara de Pablo   +9 more
doaj   +1 more source

Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. [PDF]

open access: yes, 2009
Cerebral malaria is a life-threatening complication of malaria infection. The pathogenesis of cerebral malaria is poorly defined and progress in understanding the condition is severely hampered by the inability to study in detail, ante-mortem, the ...
KEVIN N. COUPER   +11 more
core   +1 more source

Pmp Repertoires Influence the Different Infectious Potential of Avian and Mammalian Chlamydia psittaci Strains

open access: yesFrontiers in Microbiology, 2021
Chlamydia psittaci is the etiological agent of chlamydiosis in birds and can be transmitted to humans, causing severe systemic disease. C. psittaci infects a broad range of hosts; strains are isolated not only from birds but also from mammals, where they
Alison Favaroni   +4 more
doaj   +1 more source

Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy

open access: yesnpj Vaccines, 2023
Staphylococcus aureus infections are a major public health issue, and a vaccine is urgently needed. Despite a considerable promise in preclinical models, all vaccines tested thus far have failed to protect humans against S. aureus. Unlike laboratory mice,
Omid Teymournejad   +4 more
doaj   +1 more source

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