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Pathogenicity is the capacity of an organism to cause disease. During virus infections, diseases symptoms arise from two causes, direct injury caused by virus replication and the side effects of the immune response to infection. The balance between these two is variable. The majority of virus infections are asymptomatic and do not cause disease. Only a
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An Investigation of the Efficacy of Curcumin for Treatment of Alzheimer\u27s Disease [PDF]
Curcumin is the primary curcuminoid found in the rhizome of the turmeric plant (Curcuma longa), responsible for the spice’s distinctive yellow color. Research conducted within the past two decades suggests that the compound may be an effective treatment ...
Patel, Parantap
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Role of genetic aspect in pathogenesis of atopic dermatitis [PDF]
The pathogenesis of atopic dermatitis (AD) is a very complicated process that involves an intricate array of molecules. Nowadays it is generally accepted that cytokines play an important role in the progression of the clinical presentation of atopic ...
Wesserling Martyna
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Metabolomic analysis of cricket paralysis virus infection in Drosophila S2 cells reveals divergent effects on central carbon metabolism as compared with silkworm Bm5 cells [PDF]
High-throughput approaches have opened new opportunities for understanding biological processes such as persistent virus infections, which are widespread.
Meeus, Ivan+5 more
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The relationship between gut microbiota and spontaneous bacterial peritonitis in patients with liver cirrhosis - a literature review [PDF]
Gut microbiota is an essential component in the pathogenesis of liver cirrhosis and its complications. There is a direct relationship between the gut and the liver called the gutliver axis through which bacteria can reach the liver through the portal ...
Fierbinteanu Braticevici, Carmen+9 more
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Host Protease Activity on Bacterial Pathogens Promotes Complement and Antibiotic-Directed Killing
Our understanding of how the host immune system thwarts bacterial evasive mechanisms remains incomplete. Here, we show that host protease neutrophil elastase acts on Acinetobacter baumannii and Pseudomonas aeruginosa to destroy factors that prevent serum-
Shaorong Chen+6 more
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Pathogenesis of feline enteric coronavirus infection. [PDF]
Fifty-one specific pathogen-free (SPF) cats 10 weeks to 13 years of age were infected with a cat-to-cat fecal-oral passed strain of feline enteric coronavirus (FECV). Clinical signs ranged from unapparent to a mild and self-limiting diarrhea. Twenty-nine
Allen, Claire E+2 more
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Background The introduction of Bedaquiline, the first new antimycobacterial drug in over 40 years, has highlighted the critical importance of medication adherence in drug-resistant tuberculosis (DR-TB) treatment to prevent amplified drug-resistance and ...
N. Bionghi+8 more
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Body fat mass increases when energy intake exceeds energy expenditure. In the long term, a positive energy balance will result in obesity. The worldwide prevalence of obesity has increased dramatically, posing a serious threat to human health. Therefore, insight in the pathogenesis of obesity is important to identify novel prevention and treatment ...
Oussaada, Sabrina M.+7 more
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Salmonella spp. is one of the leading causes of foodborne bacterial infections, with major impacts on public health and healthcare system. Salmonella is commonly transmitted via the fecal-to-oral route, and food contaminated with the bacteria (e.g ...
Kelly Johanna Lozano-Villegas+1 more
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