Advanced Functional Materials, EarlyView.The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen +13 more
wiley +1 more source
Molecular Characterization and Pathogenicity Analysis of Novel Goose Parvovirus Isolated in Shandong Province Provide Insights into Viral Epidemic Tendency and Genetic Basis for Cross-Species Transmission and Pathogenicity Attenuation. [PDF]
Animals (Basel)Huang Y +5 more
europepmc +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
Advanced Functional Materials, EarlyView.This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson +12 more
wiley +1 more source
Rethinking the drivers of coronavirus virulence and pathogenesis; toward an understanding of the dynamic world of mutations, indels, and recombination within the alphacoronaviruses. [PDF]
mBioOlarte-Castillo XA +4 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput +5 more
wiley +1 more source
Fatty acids in filamentous pathogenic fungi: Multidimensional regulation and pathogenic mechanisms. [PDF]
VirulenceLin H, Peng Y.
europepmc +1 more source
Pathogenicity, host response and control of Cercospora leaf-spot of sugar beets
, 1932 Edgar F. Vestal
openalex +2 more sources
Organism X, Probably of the Coryne-Bacterium Group: Its Differentiation from B. Diphtheriæ and Allied Organisms; Its Pathogenicity in Man, Especially in Bronchopneumonia, and Its Relation to General Paralysis of the Insane [PDF]
, 1907 LOUIS HOAG
openalex +1 more source
Advanced Functional Materials, EarlyView.FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source