Results 261 to 270 of about 455,752 (296)

Time‐Resolved SAXS Reveals Distinct Millisecond Metal‐Induced Conformational Dynamics of Monomeric α‐Synuclein

Advanced Science, EarlyView.
Time‐resolved SAXS reveals how physiologically relevant metal ions shape the earliest conformational responses of monomeric α‐synuclein. Fe3+ induces rapid compaction, Cu2+ generates heterogeneous and partially folded ensembles, while Mn2+ and Zn2+ cause only modest changes.
Rebecca Sternke‐Hoffmann, Miriam Dos Santos Pinto, Xue Wang, Jinghui Luo   +3 more
wiley   +1 more source

Mysterious Leishmania martiniquensis parasites and their relatives of the subgenus Mundinia: Emerging pathogens reshaping our understanding of leishmaniases. [PDF]

PLoS Pathog
Volf P, Sadlova J.
europepmc   +1 more source

Genetic Landscape and Clinical Characterization of FRMD7-Related Infantile Nystagmus Based on Large In-House Datasets and Literature Review. [PDF]

Invest Ophthalmol Vis Sci
Liu S, Li S, Wang Y, Sun W, Hejtmancik JF, Zhang Q.   +5 more
europepmc   +1 more source

First molecular confirmation of Lasiodiplodia theobromae causing grapevine trunk disease in southern Egypt. [PDF]

Sci Rep
Gherbawy YA, Hassany NA, El-Dawy EGAM.
europepmc   +1 more source

Two kinds of novel reassortment H3 subtypes of avian influenza viruses: similar genetic composition, different mammalian transmission capabilities. [PDF]

Poult Sci
Han X, Zhong M, Yang Y, Fang S, Shi Y, Lin Y, Zhang X, Wu W, Wang Q, Niu B, Huang Q, Yin H, Liao M, Jia W.   +13 more
europepmc   +1 more source

Interpretable machine-learning prediction of PSEN1 missense variant pathogenicity based on multi-omics enrichment in six core Alzheimer's disease genes. [PDF]

Alzheimers Res Ther
Yang D, Wang S, Lu Y, Zhu J, Chen J, Zhang B, Cai H, Teng B, Wei R, Cen Z, Luo W.   +10 more
europepmc   +1 more source

Augmenting Diagnostic Yield From Genomic Sequencing. [PDF]

Neurol Genet
Wojcik MH, Ganesh V.
europepmc   +1 more source

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Fungal pathogens

Current Biology, 2020
Fungi are key components in global biogeochemical cycles, play important roles in manufacturing industries and biomedical research, and influence humans through their impact on global health, agriculture, and biodiversity. Fungi have been isolated from almost every environmental niche across the planet, including from air, soil, fresh water, and the ...
Sheng, Sun, Michael J, Hoy, Joseph, Heitman   +2 more
openaire   +2 more sources