Results 31 to 40 of about 210,770 (100)

The Equal Neutralizing Effectiveness of BNT162b2, ChAdOx1 nCoV-19, and Sputnik V Vaccines in the Palestinian Population

open access: yesVaccines
Since the beginning of the COVID-19 pandemic, different viral vector-based and mRNA vaccines directed against the SARS-CoV-2 “S” spike glycoprotein have been developed and have shown a good profile in terms of safety and efficacy.
Alexia Damour   +8 more
doaj   +1 more source

Structural Insights on Retroviral DNA Integration: Learning from Foamy Viruses

open access: yesViruses, 2019
Foamy viruses (FV) are retroviruses belonging to the Spumaretrovirinae subfamily. They are non-pathogenic viruses endemic in several mammalian hosts like non-human primates, felines, bovines, and equines.
Ga-Eun Lee   +4 more
doaj   +1 more source

Regulatory variants of APOBEC3 genes potentially associate with COVID-19 severity in populations with African ancestry

open access: yesScientific Reports, 2023
Since November 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused the worldwide pandemic of the coronavirus disease 2019 (COVID-19), the impact of which is huge to the lives of world populations.
Ke Zhang   +7 more
doaj   +1 more source

Improved transformation efficiency in Mycoplasma hominis enables disruption of the MIB–MIP system targeting human immunoglobulins

open access: yesMicrobiology Spectrum, 2023
The pathogenicity of Mycoplasma hominis is poorly understood, mainly due to the absence of efficient genetic tools. A polyethylene glycol-mediated transformation protocol was recently developed for the M. hominis reference strain M132 using the pMT85-Tet
Jennifer Guiraud   +7 more
doaj   +1 more source

Gene flow contributes to diversification of the major fungal pathogen Candida albicans

open access: yesNature Communications, 2018
The fungal pathogen Candida albicans can undergo a parasexual process that may contribute to genetic diversity, but its actual relevance is unclear. Here, Ropars et al. analyse the genomic sequences of 182 C.
Jeanne Ropars   +27 more
doaj   +1 more source

Effects of diisononyl phthalate on lipid metabolism in HepG2 cells

open access: yes环境与职业医学
BackgroundExposure to diisononyl phthalate (DINP), an endocrine disruptor associated with metabolic diseases and widely used in plastic products, has been linked to the development of several adverse health outcomes in the liver, including non-alcoholic ...
Xinjing WANG   +3 more
doaj   +1 more source

Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails

open access: yesRetrovirology, 2017
Background Stable insertion of the retroviral DNA genome into host chromatin requires the functional association between the intasome (integrase·viral DNA complex) and the nucleosome.
Mohamed S. Benleulmi   +19 more
doaj   +1 more source

In vitro Interactions of Pseudomonas aeruginosa With Scedosporium Species Frequently Associated With Cystic Fibrosis

open access: yesFrontiers in Microbiology, 2019
Members of the Scedosporium apiospermum species complex are the second most frequently isolated pathogens after Aspergillus fumigatus from cystic fibrosis (CF) patients with fungal pulmonary infections.
Mónika Homa   +15 more
doaj   +1 more source

A protocol for ultrastructural study of Candida albicans biofilm using transmission electron microscopy

open access: yesSTAR Protocols, 2022
Summary: This protocol describes how to analyze C. albicans biofilm using transmission electron microscopy. We present two approaches to observe the ultrastructure of fungal cells within unperturbed biofilms, as well as an immunogold labeling procedure ...
Thierry Mourer   +4 more
doaj  

Uncharted territories in the discovery of antifungal and antivirulence natural products from bacteria

open access: yesComputational and Structural Biotechnology Journal, 2021
Many fungi can cause deadly diseases in humans, and nearly every human will suffer from some kind of fungal infection in their lives. Only few antifungals are available, and some of these fail to treat intrinsically resistant species and the ever ...
Raghav Vij, Bernhard Hube, Sascha Brunke
doaj  

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