Results 31 to 40 of about 256,194 (269)

Bhalin, an Essential Cytoskeleton-Associated Protein of Trypanosoma brucei Linking TbBILBO1 of the Flagellar Pocket Collar with the Hook Complex

Microorganisms, 2021
Background: In most trypanosomes, endo and exocytosis only occur at a unique organelle called the flagellar pocket (FP) and the flagellum exits the cell via the FP.
Christine E. Broster Reix, Célia Florimond, Anne Cayrel, Amélie Mailhé, Corentin Agnero-Rigot, Nicolas Landrein, Denis Dacheux, Katharina Havlicek, Mélanie Bonhivers, Brooke Morriswood, Derrick R. Robinson   +10 more
doaj   +1 more source

Pathogen Sensors [PDF]

Sensors, 2009
The development of sensors for detecting foodborne pathogens has been motivated by the need to produce safe foods and to provide better healthcare. However, in the more recent times, these needs have been expanded to encompass issues relating to biosecurity, detection of plant and soil pathogens, microbial communities, and the environment. The range of
openaire   +4 more sources

A Novel Hybrid Iron Regulation Network Combines Features from Pathogenic and Nonpathogenic Yeasts

mBio, 2016
Iron is an essential micronutrient for both pathogens and their hosts, which restrict iron availability during infections in an effort to prevent microbial growth.
Franziska Gerwien, Abu Safyan, Stephanie Wisgott, Fabrice Hille, Philipp Kaemmer, Jörg Linde, Sascha Brunke, Lydia Kasper, Bernhard Hube   +8 more
doaj   +1 more source

An interspecies regulatory network inferred from simultaneous RNA-seq of Candida albicans invading innate immune cells

Frontiers in Microbiology, 2012
The ability to adapt to diverse micro-environmental challenges encountered within a host is of pivotal importance to the opportunistic fungal pathogen C. albicans. We have quantified C.albicans and M. musculus gene expression dynamics during phagocytosis
Lanay eTierney, Jörg eLinde, Sebastian eMüller, Sascha eBrunke, Sascha eBrunke, Juan Camilo Molina, Bernhard eHube, Bernhard eHube, Ulrike eSchöck, Reinhard eGuthke, Karl eKuchler   +10 more
doaj   +1 more source

Chemical Characterization and Leishmanicidal Activity In Vitro and In Silico of Natural Products Obtained from Leaves of Vernonanthura brasiliana (L.) H. Rob (Asteraceae)

Metabolites, 2023
Vernonanthura brasiliana (L.) H. Rob is a medicinal plant used for the treatment of several infections. This study aimed to evaluate the antileishmanial activity of V. brasiliana leaves using in vitro and in silico approaches. The chemical composition of
Yuri Nascimento Fróes, João Guilherme Nantes Araújo, Joyce Resende dos Santos Gonçalves, Milena de Jesus Marinho Garcia de Oliveira, Gustavo Oliveira Everton, Victor Elias Mouchrek Filho, Maria Raimunda Chagas Silva, Luís Douglas Miranda Silva, Lucilene Amorim Silva, Lídio Gonçalves Lima Neto, Renata Mondêgo de Oliveira, Mylena Andréa Oliveira Torres, Luís Cláudio Nascimento da Silva, Alberto Jorge Oliveira Lopes, Amanda Silva dos Santos Aliança, Cláudia Quintino da Rocha, Joicy Cortez de Sá Sousa   +16 more
doaj   +1 more source

Spatiotemporal Analysis and Deep Learning-Based Prediction of Air Pollution in China, 2015–2024

Atmosphere
Air quality in China has markedly improved over the past decade, yet pollution levels remain high and continue to threaten public health. This study analyzed the spatiotemporal variations in six air pollutants (PM2.5, PM10, SO2, NO2, O3, CO) across seven
Kai Tan, Qianjun Ren, Yiting Huo, Lu Ran, Xiaofang Xu, Li Cao, Qianying Xiang, Huirong Duan, Shuhan Wang, Jisheng Nie, Xiujuan Yang   +10 more
doaj   +1 more source

The Dual Function of the Fungal Toxin Candidalysin during Candida albicans—Macrophage Interaction and Virulence

Toxins, 2020
The dimorphic fungus Candida albicans is both a harmless commensal organism on mucosal surfaces and an opportunistic pathogen. Under certain predisposing conditions, the fungus can overgrow the mucosal microbiome and cause both superficial and life ...
Annika König, Bernhard Hube, Lydia Kasper   +2 more
doaj   +1 more source

Candidalysin Is the Hemolytic Factor of Candida albicans

Toxins, 2022
Candida albicans produces an important virulence factor, the hypha-associated Ece1-derived secreted peptide toxin candidalysin, which is crucial for the establishment of mucosal and systemic infections. C.
Selene Mogavero, Sarah Höfs, Alexa N. Lauer, Rita Müller, Sascha Brunke, Stefanie Allert, Franziska Gerwien, Sabrina Groth, Edward Dolk, Duncan Wilson, Thomas Gutsmann, Bernhard Hube   +11 more
doaj   +1 more source

Antibiotics as a Stressing Factor Triggering the Harboring of Helicobacter pylori J99 within Candida albicans ATCC10231

Pathogens, 2021
First-line treatment for Helicobacter pylori includes amoxicillin and clarithromycin or metronidazole plus a proton pump inhibitor. Treatment failure is associated with antibiotic resistance and possibly also with internalization of H.
Kimberly Sánchez-Alonzo, Libnny Belmar, Cristian Parra-Sepúlveda, Humberto Bernasconi, Víctor L. Campos, Carlos T. Smith, Katia Sáez, Apolinaria García-Cancino   +7 more
doaj   +1 more source

AMPK in Pathogens [PDF]

, 2016
During host-pathogen interactions, a complex web of events is crucial for the outcome of infection. Pathogen recognition triggers powerful cellular signaling events that is translated into the induction and maintenance of innate and adaptive host immunity against infection.
Mesquita, Inês, Moreira, Diana, Sampaio-Marques, Belém, Laforge, Mireille, Cordeiro-Da-Silva, Anabela, Ludovico, Paula, Estaquier, Jérôme, Silvestre, Ricardo   +7 more
openaire   +4 more sources