Results 141 to 150 of about 4,548,713 (378)

STUDY REGARDING THE NEUROPSYCHIC PATHOLOGY IMPLICATIONS IN PERIODONTAL PATHOLOGY

open access: yesRomanian Journal of Oral Rehabilitation, 2014
Introduction: Epilepsy, in all its forms, must be known by the dental specialists who always can encounter an epileptic seizure when treating such patients.
Liliana Păsărin   +7 more
doaj  

Deep learning for digital pathology image analysis: A comprehensive tutorial with selected use cases

open access: yesJournal of Pathology Informatics, 2016
Background: Deep learning (DL) is a representation learning approach ideally suited for image analysis challenges in digital pathology (DP). The variety of image analysis tasks in the context of DP includes detection and counting (e.g., mitotic events ...
A. Janowczyk, A. Madabhushi
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy. [PDF]

open access: yes, 2018
Alzheimer's disease (AD), the most common form of dementia, is characterized by the abnormal accumulation of amyloid plaques and hyperphosphorylated tau aggregates, as well as microgliosis. Hemizygous missense variants in Triggering Receptor Expressed on
Akassoglou, Katerina   +15 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Effect of a rigid ankle-foot orthosis on hamstring length in children with hemiplagia [PDF]

open access: yes, 2002
Eighteen children with hemiplegia, mean age 8 years 5 months, underwent gait analysis and musculoskeletal modelling using specially designed software. The maximum lengths of the hamstrings were determined for each child walking in and out of an ankle–
Baker, RJ   +4 more
core  

Home - About - Disclaimer - Privacy