Results 61 to 70 of about 4,561,975 (395)
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
An Exploration of Racial/Ethnic Differences in the Association between Perfectionism and Disordered Eating in College Students [PDF]
, 2019 Perfectionism is a robust risk factor for eating disorders (EDs). Although individually-oriented dimensions of perfectionism are strongly related to eating pathology, less is known about the contribution of parent-oriented dimensions, specifically ...
Burnette, C Blair +2 more
core +1 more source
Macrophage autophagy in atherosclerosis [PDF]
, 2013 Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Carnuccio, R. +5 more
core +2 more sources
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Pannexin1 channels in the liver: an open enemy
Frontiers in Cell and Developmental Biology, 2023 Pannexin1 proteins form communication channels at the cell plasma membrane surface, which allow the transfer of small molecules and ions between the intracellular compartment and extracellular environment.
Raf Van Campenhout +7 more
doaj +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
The Journal of Pathology: Clinical Research, 2020 The human microbiome can play key roles in disease, and diagnostic testing will soon have the ability to examine these roles in the context of clinical applications.
Caitlin A Selway +2 more
doaj +1 more source
Frontiers in Endocrinology, 2020 Pheochromocytomas and paragangliomas (PHEO/PGL) are rare but occasionally life-threatening neoplasms, and are potentially malignant according to WHO classification in 2017.
Yuto Yamazaki +14 more
doaj +1 more source
Aging display's effect on interpretation of digital pathology slides
, 2015 It is our conjecture that the variability of colors in a pathology image effects the interpretation of pathology cases, whether it is diagnostic accuracy, diagnostic confidence, or workflow efficiency. In this paper, digital pathology images are analyzed
Avanaki, Ali R. N. +6 more
core +1 more source