Results 61 to 70 of about 3,557,764 (353)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Updates in ophthalmic pathology

Indian Journal of Ophthalmology, 2017
Ophthalmic pathology has a long history and rich heritage in the field of ophthalmology. This review article highlights updates in ophthalmic pathology that have developed significantly through the years because of the efforts of committed individuals ...
Pia R Mendoza, Hans E Grossniklaus
doaj   +1 more source

Brain Age Revisited: Investigating the State vs. Trait Hypotheses of EEG-derived Brain-Age Dynamics with Deep Learning [PDF]

arXiv, 2023
The brain's biological age has been considered as a promising candidate for a neurologically significant biomarker. However, recent results based on longitudinal magnetic resonance imaging data have raised questions on its interpretation. A central question is whether an increased biological age of the brain is indicative of brain pathology and if ...
arxiv  

Underactive bladder - an underestimated entity [PDF]

, 2020
Introduction. The concept of underactive bladder is relatively new. Currently there is no generally accepted definition of this pathology. Diagnosis depends on urodynamic findings, and symptoms are usually rare and intricated with the symptoms of other ...
Bratu, Ovidiu Gabriel, Bungau, Simona, Dan, Spinu Arsenie, Gherghiceanu, Florentina, Ionita-Radu, Florentina, Marcu, Dragos Radu, Mischianu, Dan, Stanciu, Adina Elena, Stanescu, Ana Maria Alexandra   +8 more
core   +1 more source

AAV-mediated transcription factor EB (TFEB) gene delivery ameliorates muscle pathology and function in the murine model of Pompe Disease [PDF]

, 2017
Pompe disease (PD) is a metabolic myopathy due to acid alpha-glucosidase deficiency and characterized by extensive glycogen storage and impaired autophagy.
Alvino, Filomena Grazia, Auricchio, Alberto, Ballabio, Andrea, Carrella, Alessandra, De Leonibus, Elvira, Diez-roux, Graciana, Gatto, Francesca, Iacobellis, Francesca, Nusco, Edoardo, Parenti, Giancarlo, Polishchuk, Elena, Polishchuk, Roman, Rossi, Barbara, Tarallo, Antonietta   +13 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Associations of Social Vulnerability Index With Pathologic Myocardial Findings at Autopsy

Frontiers in Cardiovascular Medicine, 2021
Background: Social vulnerability is an important determinant of cardiovascular health. Prior investigations have shown strong associations of social determinants of health with cardiovascular risk factors, imaging findings, and clinical events.
Ashwin Sunderraj, Ashwin Sunderraj, Adovich Rivera, Adovich Rivera, Meghna Gaddam, Meghna Gaddam, Sarah Kim, Sarah Kim, Juan McCook, Juan McCook, Janelle O'Neal, Janelle O'Neal, Jon Lomasney, Donald M. Lloyd-Jones, Donald M. Lloyd-Jones, Yvonne Baumer, Tiffany M. Powell-Wiley, Tiffany M. Powell-Wiley, Matthew J. Feinstein, Matthew J. Feinstein, Matthew J. Feinstein, Matthew J. Feinstein   +21 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Expert consensus on precision detection of intrahepatic cholangiocarcinoma (2024 edition)

Zhongguo Linchuang Yixue
Intrahepatic cholangiocarcinoma (ICC) is a highly heterogeneous tumor, and molecular profiling serves as the foundation for personalized treatment of ICC.
Pathology Group, Chinese Society of Liver Cancer of Chinese Anti-Cancer Association; Liver Pathology Group, Chinese Society of Pathology of Chinese Anti-Cancer Association; Tumor Pathology Committee of Shanghai Anti-Cancer Association, Shanghai 200032, China
doaj   +1 more source

An updated review on bluetongue virus: epidemiology, pathobiology, and advances in diagnosis and control with special reference to India

Veterinary Quarterly, 2020
Bluetongue (BT) is an economically important, non-contagious viral disease of domestic and wild ruminants. BT is caused by BT virus (BTV) and it belongs to the genus Orbivirus and family Reoviridae.
Mani Saminathan, Karam Pal Singh, Jaynudin Hajibhai Khorajiya, Murali Dinesh, Sobharani Vineetha, Madhulina Maity, AT Faslu Rahman, Jyoti Misri, Yashpal Singh Malik, Vivek Kumar Gupta, Raj Kumar Singh, Kuldeep Dhama   +11 more
doaj   +1 more source