Results 61 to 70 of about 4,237,903 (401)
Proceedings of the National Academy of Sciences of the United States of America, 1986 A monoclonal antibody to the microtubule-associated protein tau (tau) labeled some neurofibrillary tangles and plaque neurites, the two major locations of paired-helical filaments (PHF), in Alzheimer disease brain.
I. Grundke‐Iqbal +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Veterinary Quarterly, 2021 Background Brucellosis of goats is caused by Brucella melitensis. It is a re-emerging zoonotic disease in many countries due to transmission from domestic animals and wildlife such as ibex, deer and wild buffaloes.
Mazlina Mazlan +5 more
doaj +1 more source
Unsupervised Pathology Image Segmentation Using Representation Learning with Spherical K-means [PDF]
Proc. SPIE 10581, Medical Imaging 2018: Digital Pathology, 1058111
(6 March 2018), 2018 This paper presents a novel method for unsupervised segmentation of pathology images. Staging of lung cancer is a major factor of prognosis. Measuring the maximum dimensions of the invasive component in a pathology images is an essential task. Therefore, image segmentation methods for visualizing the extent of invasive and noninvasive components on ...
arxiv +1 more source
AAV-mediated transcription factor EB (TFEB) gene delivery ameliorates muscle pathology and function in the murine model of Pompe Disease [PDF]
, 2017 Pompe disease (PD) is a metabolic myopathy due to acid alpha-glucosidase deficiency and characterized by extensive glycogen storage and impaired autophagy.
Alvino, Filomena Grazia +13 more
core +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Hendra Virus Infection in Dog, Australia, 2013
Emerging Infectious Diseases, 2015 Hendra virus occasionally causes severe disease in horses and humans. In Australia in 2013, infection was detected in a dog that had been in contact with an infected horse.
Peter D. Kirkland +10 more
doaj +1 more source
Benchmarking Self-Supervised Learning on Diverse Pathology Datasets [PDF]
arXiv, 2022 Computational pathology can lead to saving human lives, but models are annotation hungry and pathology images are notoriously expensive to annotate. Self-supervised learning has shown to be an effective method for utilizing unlabeled data, and its application to pathology could greatly benefit its downstream tasks.
arxiv
Pathology Segmentation using Distributional Differences to Images of Healthy Origin [PDF]
In International MICCAI Brainlesion Workshop, pp. 228-238.
Springer, Cham, 2018, 2018 Fully supervised segmentation methods require a large training cohort of already segmented images, providing information at the pixel level of each image. We present a method to automatically segment and model pathologies in medical images, trained solely on data labelled on the image level as either healthy or containing a visual defect.
arxiv +1 more source
Life After Being a Pathology Department Chair II: Lessons Learned. [PDF]
, 2017 The 2016 Association of Pathology Chairs annual meeting featured a discussion group of Association of Pathology Chairs senior fellows (former chairs of academic departments of pathology who have remained active in Association of Pathology Chairs) that ...
Bailey, David N. +4 more
core +2 more sources