Results 31 to 40 of about 5,776,246 (295)

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature, 2008
Human cancer cells typically harbour multiple chromosomal aberrations, nucleotide substitutions and epigenetic modifications that drive malignant transformation.
R. McLendon, A. Friedman, D. Bigner, Erwin G. Van Meir, D. Brat, Gena M Mastrogianakis, J. Olson, T. Mikkelsen, N. Lehman, K. Aldape, W. Yung, O. Bogler, J. Weinstein, S. Vandenberg, M. Berger, M. Prados, D. Muzny, M. Morgan, S. Scherer, A. Sabo, L. Nazareth, L. Lewis, O. Hall, Yiming Zhu, Yanru Ren, Omar Alvi, Jiqiang Yao, A. Hawes, S. Jhangiani, G. Fowler, A. Lucas, C. Kovar, Andrew Cree, H. Dinh, J. Santibanez, Vandita Joshi, M. Gonzalez-Garay, Christopher A. Miller, A. Milosavljevic, L. Donehower, D. Wheeler, R. Gibbs, K. Cibulskis, C. Sougnez, T. Fennell, Scott Mahan, Jane Wilkinson, L. Ziaugra, R. Onofrio, Toby Bloom, R. Nicol, K. Ardlie, J. Baldwin, S. Gabriel, E. Lander, L. Ding, R. Fulton, M. McLellan, J. Wallis, D. Larson, Xiaoqi Shi, R. Abbott, L. Fulton, Ken Chen, D. Koboldt, M. Wendl, R. Meyer, Yuzhu Tang, Ling Lin, John R. Osborne, Brian H. Dunford-Shore, T. Miner, K. Delehaunty, C. Markovic, Gary W. Swift, W. Courtney, C. Pohl, S. Abbott, Amy E. Hawkins, Shin Leong, C. Haipek, Heather K. Schmidt, M. Wiechert, T. Vickery, S. Scott, D. Dooling, A. Chinwalla, G. Weinstock, E. Mardis, R. Wilson, G. Getz, W. Winckler, R. Verhaak, M. Lawrence, Michael J. T. O’Kelly, James Robinson, Gabriele Alexe, R. Beroukhim, S. Carter, Derek Y. Chiang, Josh Gould, Supriya Gupta, Joshua M. Korn, C. Mermel, J. Mesirov, S. Monti, Huy L. Nguyen, Melissa Parkin, Michael Reich, Nicolas Stransky, B. Weir, L. Garraway, T. Golub, M. Meyerson, L. Chin, A. Protopopov, Jianhua Zhang, I. Perna, S. Aronson, N. Sathiamoorthy, Georgi Ren, Jun Yao, W. Wiedemeyer, Hyun Soo Kim, Won Kong Sek, Yonghong Xiao, I. Kohane, J. Seidman, P. Park, R. Kucherlapati, P. Laird, L. Cope, J. Herman, D. Weisenberger, F. Pan, D. V. Berg, L. V. Neste, Mingyu Joo, Kornel E. Schuebel, S. Baylin, D. Absher, Jun Z. Li, Audrey M. Southwick, Shannon T. Brady, A. Aggarwal, Tisha Chung, G. Sherlock, J. Brooks, R. Myers, P. Spellman, E. Purdom, L. Jakkula, A. Lapuk, H. Marr, S. Dorton, Gi Choi Yoon, Ju Han, Amrita Ray, V. Wang, S. Durinck, M. Robinson, Nicholas J. Wang, K. Vranizan, V. Peng, E. V. Name, G. Fontenay, J. Ngai, J. Conboy, B. Parvin, H. Feiler, T. Speed, J. Gray, C. Brennan, N. Socci, A. Olshen, B. Taylor, A. Lash, N. Schultz, B. Reva, Yevgeniy Antipin, Alexey Stukalov, Benjamin E. Gross, E. Cerami, Qingqing Wei, L. Qin, V. Seshan, L. Villafania, Magali Cavatore, L. Borsu, A. Viale, W. Gerald, C. Sander, M. Ladanyi, C. Perou, D. Hayes, M. D. Topal, K. Hoadley, Yuan Qi, S. Balu, Yan Shi, Junyuan Wu, R. Penny, M. Bittner, T. Shelton, E. Lenkiewicz, S. Morris, D. Beasley, Sheri Sanders, A. Kahn, R. Sfeir, Jessica Chen, D. Nassau, Larry Feng, E. Hickey, A. Barker, D. Gerhard, J. Vockley, C. Compton, J. Vaught, P. Fielding, M. Ferguson, C. Schaefer, Jinghui Zhang, Subha Madhavan, K. Buetow, F. Collins, P. Good, M. Guyer, B. Ozenberger, Jane L. Peterson, E. Thomson   +230 more
semanticscholar   +1 more source

Development and Pilot Study of a Pediatric Screening for Feeding and Swallowing Disorders in Infants and Children: The Pediatric Screening–Priority Evaluation Dysphagia (PS–PED)

Children, 2023
Feeding and swallowing disorders (FSD) are common during childhood, with a prevalence of 85% in children with neurodevelopmental disorders. A comprehensive screening is essential to identify FSD and improve health outcomes in a clinical setting.
Antonella Cerchiari, Marco Tofani, Carolina Giordani, Silvia Franceschetti, Eleonora Capuano, Francesca Pizza, Gessica Della Bella, Massimiliano Raponi, Giorgia Biondo   +8 more
doaj   +1 more source

Multimorbidity and determinants for initiating outpatient trajectories: A population-based study

BMC Public Health, 2023
Introduction Individuals with multimorbidity often receive high numbers of hospital outpatient services in concurrent trajectories. Nevertheless, little is known about factors associated with initiating new hospital outpatient trajectories; identified as
Cathrine Bell, Anders Prior, Charlotte Weiling Appel, Anne Frølich, Asger Roer Pedersen, Peter Vedsted   +5 more
doaj   +1 more source

The Efficacy of the Global Intensive Feeding Therapy on Feeding and Swallowing Abilities in Children with Autism Spectrum Disorder: A Pilot Study

Children, 2023
The present investigation aims to explore the efficacy of Global Intensive Feeding Therapy (GIFT) on feeding and swallowing abilities in children with autism spectrum disorder (ASD).
Antonella Cerchiari, Carolina Giordani, Silvia Franceschetti, Serena Mazzafoglia, Flavia Carosi, Francesca Pizza, Gessica Della Bella, Massimiliano Raponi, Marco Tofani   +8 more
doaj   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein, Melissa J. Rose, Scott Moerdler, Richard Ho   +3 more
wiley   +1 more source

One size does not fit all: universal cuff overestimates oscillometric blood pressure in persons with large arm circumference

Blood Pressure
Objective Some brachial cuffs for oscillometric blood pressure (BP) measurement are claimed to cover a wide range of upper-arm circumferences; however, their validation is rarely conducted.
Katrine Bovien Gørlitz, Esben Laugesen, Christian Trolle, Louise Jung Nørgård, Siv Lajlev, Michele Colombo, Mette Bohl, Klavs Würgler Hansen   +7 more
doaj   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga, Angela Lopez‐Cortes, Reem Al‐Saadi, Suzanne Tugnait, Kristina Dzhuma, Catriona Duncan, Gordan Vujanic, Tanzina Chowdhury, Claudia Allemani, Michel P. Coleman, Kathy Pritchard‐Jones, the Children's Cancer and Leukaemia Group (CCLG) Renal Tumour Special Interest Group, Hugh Bishop, Anthony McCarthy, Pamela Kearns, Helen Rees, Amos Burke, Meriel Jenney, Jane Pears, Hamish Wallace, Milind Ronghe, Tanzina Chowdhury, Susan Picton, Emma Ross, Lisa Howell, Bernadette Brennan, Gail Halliday, Richard Grundy, Shaun Wilson, Sucheta Vaidya, Daniel Yeomanson, Jessica Bate, Vesna Pavasovic, Jessica Bate, Sabine Irtan, Jesper Brok, Minou Oostveen, Kristina Dzhuma, Mark Weeks, Richard Williams, Mark Powis, Max Pachl, Bruce Okoye, Naima Smeulders, Gordan Vujanic, Oystein Olsen, Tom Watson, Susan Shelmerdine, Dan Saunders, Angela Lopez-Cortes, Taryn Treger, Tom Jackson, Suzanne Tugnait, Lisa Howell, Tanzina Chowdhury, Sam Behjati, Angela Polanco   +56 more
wiley   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Psychological Safety Among Interprofessional Pediatric Oncology Teams in Germany: A Nationwide Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn, Anna‐Lena Herbach, Christian Bock, Katharina Fleig, Urs Mücke   +4 more
wiley   +1 more source

Understanding pre-service teacher education discourses in Communities of Practice: A reflection from an intervention in rural South Africa

Perspectives in Education, 2012
Drawing on an evaluation experience of a teacher education preparation project in a rural area of South Africa, this paper attempts to explore the possibility of using Communities of Practice (CoP) in teacher preparation.
Faisal Islam
doaj   +3 more sources