Results 31 to 40 of about 7,950,605 (408)
BMC Public Health, 2023 Background South Africa has a complex range of historical, social, political, and economic factors that have shaped fatherhood. In the context of the Bukhali randomised controlled trial with young women in Soweto, South Africa, a qualitative study was ...
Catherine E. Draper +8 more
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The representative concentration pathways: an overview
, 2011 This paper summarizes the development process and main characteristics of the Representative Concentration Pathways (RCPs), a set of four new pathways developed for the climate modeling community as a basis for long-term and near-term modeling ...
D. P. Vuuren +14 more
semanticscholar +1 more source
Pathways to Parkinsonism [PDF]
Neuron, 2003 A novel gene for Parkinson's disease (PD), DJ-1, has been identified that encodes a multifunctional product with several known protein-protein interactions and effects on gene expression. Here, I outline how it is possible to construct hypotheses that place DJ-1 in different relationships to the other known PD genes, alpha-synuclein and parkin.
openaire +3 more sources
Metabolomics, Pathway Regulation, and Pathway Discovery [PDF]
Journal of Biological Chemistry, 2011 Metabolomics is a data-based research strategy, the aims of which are to identify biomarker pictures of metabolic systems and metabolic perturbations and to formulate hypotheses to be tested. It involves the assay by mass spectrometry or NMR of many metabolites present in the biological system investigated.
Sushabhan Sadhukhan +3 more
openaire +3 more sources
Total Lipopolysaccharide from the Human Gut Microbiome Silences Toll-Like Receptor Signaling
mSystems, 2017 Cohabitation of microbial communities with the host enables the formation of a symbiotic relationship that maintains homeostasis in the gut and beyond. One prevailing model suggests that this relationship relies on the capacity of host cells and tissues ...
Eva d’Hennezel +3 more
doaj +1 more source
Children, 2023 Feeding and swallowing disorders (FSD) are common during childhood, with a prevalence of 85% in children with neurodevelopmental disorders. A comprehensive screening is essential to identify FSD and improve health outcomes in a clinical setting.
Antonella Cerchiari +8 more
doaj +1 more source
BMC Health Services Research, 2019 Background With an extensive rise in the number of acute patients and increases in both admissions and readmissions, hospitals are at times overcrowded and under immense pressure and this may challenge patient safety.
Cathrine Bell +3 more
doaj +1 more source
Scientific Reports, 2022 Although appendicular skeletal muscle mass (ASM) and handgrip strength (HGS) are key components of sarcopenia, their underlying biological mechanisms remain poorly understood.
Siphiwe N. Dlamini +7 more
doaj +1 more source
Evolutionary accessibility of mutational pathways [PDF]
, 2011 Functional effects of different mutations are known to combine to the total effect in highly nontrivial ways. For the trait under evolutionary selection (`fitness'), measured values over all possible combinations of a set of mutations yield a fitness ...
de Visser, J. Arjan G. M. +3 more
core +5 more sources
Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets
Signal Transduction and Targeted Therapy, 2021 The arachidonic acid (AA) pathway plays a key role in cardiovascular biology, carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc.
Bei Wang +8 more
semanticscholar +1 more source