Results 161 to 170 of about 3,264,086 (339)

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

A novel nerve block and anatomy workshop for emergency medicine residents: A pilot study

Anatomical Sciences Education, EarlyView.
Abstract Construct a workshop for emergency medicine (EM) residents to learn ultrasound‐guided regional anesthesia (UGRA) procedures and build confidence in performing those procedures. Use pre‐ and post‐workshop knowledge and confidence surveys to determine workshop effectiveness.
Geoffery D. Fernquist, Derek Harmon, Lauren D. Branditz, Andrew Kendle, Melissa M. Quinn   +4 more
wiley   +1 more source

Bowtie Technique for Arthroscopic Hip Inversion Labral Repair

Arthroscopy Techniques, EarlyView.
Abstract Various suture techniques for arthroscopic hip labral repair have been described to address labral pathology. However, optimal restoration of the labral suction seal relies on proper tension and control of the labral tissue during the repair.
Mathew Park, Spencer Sims, Tyler Bilden, Grace Peterson, Travis Menge   +4 more
wiley   +1 more source

Patient‐controlled oral analgesia versus nurse‐controlled parenteral analgesia after caesarean section: a randomised controlled trial

Anaesthesia, 2016
A. Bonnal, A. Dehon, N. Nagot, V. Macioce, E. Nogué, E. Morau   +5 more
semanticscholar   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Epidural analgesia versus intravenous patient-controlled analgesia following minimally invasive pectus excavatum repair: a systematic review and meta-analysis.

Journal of Pediatric Surgery, 2014
Andrea Stroud, D. Tulanont, T. E. Coates, P. Goodney, Daniel P. Croitoru   +4 more
semanticscholar   +1 more source

Community pharmacists' practices and perspectives on deprescribing high‐risk psychotropic medicines: National survey findings

British Journal of Clinical Pharmacology, EarlyView.
Aim To explore the practices, confidence and perspectives of community pharmacists in deprescribing high‐risk psychotropic medicines, including opioid analgesics, benzodiazepine, gabapentinoids and medicinal cannabis. Methods An anonymous, cross‐sectional national online survey was conducted between January and April 2025 among Australian community ...
Monica Jung, Louisa Picco, Aili V. Langford, Rose Laing, Jana Dostal, Suzanne Nielsen   +5 more
wiley   +1 more source

A comparison between subpleural patient-controlled analgesia by bupivacaine and intermittent analgesia in post-operative thoracotomy: A double-blind randomized clinical trial

Journal of Research in Medical Sciences, 2011
Background: The efficacy of subpleural analgesia to reduce postoperative pain intensity in patients after lateral thoracotomy is controversial. In this study, we demonstrated the efficacy of two types of subpleural analgesia.
Vahid Goharian, Sayyed Abbas Tabatabaee, Sayyed MozafarHashemi, Gholamreza Mohajery, Mohammad Arash Ramezani, Fatemeh Shabani, Zahra MotevalliEmami   +6 more
doaj  

Patient controlled opioid analgesia versus non-patient controlled opioid analgesia for postoperative pain.

Cochrane Database of Systematic Reviews, 2015
E. McNicol, McKenzie C. Ferguson, J. Hudcova   +2 more
semanticscholar   +1 more source