Results 151 to 160 of about 2,863,004 (297)

Feasibility of Collecting Multiple Patient-Reported Outcome Measures Alongside the Dutch Arthroplasty Register [PDF]

, 2019
C. Tilbury, Claudia S. Leichtenberg, Bart L. Kaptein, Lennard A. Koster, S. H. M. Verdegaal, Ron Onstenk, Henrike M. J. van der Linden-van der Zwaag, Rover Krips, H. H. Kaptijn, Stephan B W Vehmeijer, Willem-Jan C M Marijnissen, J. Meesters, Stephanie M. van Rooden, Ronald Brand, Rob G. H. H. Nelissen, Maaike G. J. Gademan, T. P. M. Vliet Vlieland   +16 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Quality of Postoperative Pain Management after Midfacial Fracture Repair—An Outcome-oriented Study [PDF]

, 2015
Objectives There is a lack of literature regarding the procedure-specific quality of acute postoperative pain management after midfacial fracture repair.
Djedovic, Gabriel, Gomez-Dammeier, Marta, Guentsch, Arndt, Meissner, Winfried, Peisker, Andre, Raschke, Gregor F., Rieger, Ulrich M., Schaefer, Oliver, Venth, Eric   +8 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Patient reported outcomes used in clinical trials and core outcome sets for individuals with genetic intellectual disability: a scoping review

Journal of Neurodevelopmental Disorders
Background The impact of genetic intellectual disability (GID) on daily life is significant. To better understand the impact of GID, it is essential to measure relevant patient reported outcomes (PROs).
Nadia Y. van Silfhout, Maud M. van Muilekom, Clara D. van Karnebeek, Joost G. Daams, Lotte Haverman, Agnies M. van Eeghen   +5 more
doaj   +1 more source

Multidimensional, patient-reported outcome after posterior fossa decompression in 79 patients with Chiari malformation type I [PDF]

, 2019
Jan De Vlieger, Joost Dejaegher, Frank Van Calenbergh   +2 more
openalex   +1 more source

Deep wrist injuries from suicide attempts vs. accidents do not differ regarding sensorimotor outcome, but regarding patient-reported outcome measures

, 2021
Nico Matzkeit, Tobias Kisch, Annika Waldmann, Ulrich Schweiger, P. Mailänder, Anna Lisa Westermair   +5 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Development and validation of clinical implementation methods for patient-reported outcomes in Japanese multi-center palliative care units

Journal of Patient-Reported Outcomes
Background Patient-Reported Outcomes (PROs) are recommended for use in clinical oncology. However, they are not routinely used in professional palliative care practices in Japan.
Nao Ito, Azusa Sato, Kana Takeuchi, Tomoko Shigeno, Hiroko Sasaki, Maho Aoyama, Mitsunori Miyashita   +6 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source