Results 161 to 170 of about 7,712,957 (388)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Differences in patient-reported processes and outcomes between men and women with myocardial infarction [PDF]

, 2000
Kenneth E. Covinsky, Mary‐Margaret Chren, Dwain L. Harper, Lynne E. Way, Gary E. Rosenthal   +4 more
openalex   +1 more source

Development of the National Cancer Institute's patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE).

Journal of the National Cancer Institute, 2014
The standard approach for documenting symptomatic adverse events (AEs) in cancer clinical trials involves investigator reporting using the National Cancer Institute's (NCI's) Common Terminology Criteria for Adverse Events (CTCAE).
E. Basch, B. Reeve, S. Mitchell, S. Clauser, L. Minasian, A. Dueck, T. Mendoza, J. Hay, T. Atkinson, A. Abernethy, D. Bruner, C. Cleeland, J. Sloan, Ram Chilukuri, Paul Baumgartner, A. Denicoff, D. S. St Germain, A. O'Mara, Alice Chen, J. Kelaghan, A. Bennett, L. Sit, L. Rogak, A. Barz, D. Paul, D. Schrag   +25 more
semanticscholar   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Pregnancy outcome in a patient with chronic malnutrition: Case report [PDF]

, 2000
Michael P. O’Connell, Oriole Wilson, E. A. Masson, Stephen W. Lindow   +3 more
openalex   +1 more source

A systematic review of weight-related communication trainings for physicians: What do we know and how can we inform future development of training programs? [PDF]

, 2017
It is reported that physicians lack training to address weight-related concerns with patients. To overcome this, training programs have been implemented in medical settings to prepare physicians to have conversations with patients. However, it is unclear
LaRose, Jessica G, Reading, Jean M, Snell, Morgan   +2 more
core   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Paving the way for patient centricity in real-world evidence (RWE): Qualitative interviews to identify considerations for wider implementation of patient-reported outcomes in RWE generation

Heliyon, 2023
Objectives: Real-world evidence (RWE) generation can be enhanced by including patient-reported outcomes (PROs). Methods for collecting and using PRO data in the real-world setting are currently underdeveloped and there is no international guidance ...
Konrad Maruszczyk, Christel McMullan, Olalekan Lee Aiyegbusi, Thomas Keeley, Roger Wilson, Philip Collis, Catherine Bottomley, Melanie J. Calvert   +7 more
doaj  

Is the Use of Crinone for Support of the Luteal Phase Detrimental to Pregnancy Outcome After Transfer of Non-Cryopreserved Embryos in Good Prognosis Patients? A Preliminary Report [PDF]

, 2000
Christos Coutifaris, Pasquale Patrizio, Deborah J. Schafer, S. Bunso, J. Bucci, Kurt T. Barnhart   +5 more
openalex   +1 more source

Utilizing Digital Health to Collect Electronic Patient-Reported Outcomes in Prostate Cancer: Single-Arm Pilot Trial [PDF]

, 2020
Background: Measuring patient-reported outcomes (PROs) requires an individual’s perspective on their symptoms, functional status, and quality of life. Digital health enables remote electronic PRO (ePRO) assessments as a clinical decision support tool to ...
Dicker, MD, PhD, Adam, Gressen, MD, Eric, Jim, PhD, Heather, Leiby, PhD, Benjamin, Tran, MS, Christine, Williams, MD, Noelle   +5 more
core   +1 more source