Results 181 to 190 of about 2,582,753 (309)

High Versus Low Radiographic Burden Odontogenic Sinusitis: Culture, Histopathology, and Patient-Reported Outcomes. [PDF]

Laryngoscope Investig Otolaryngol
Ebbert LE, Kumar N, Lal D, Miglani A, Marino MJ.   +4 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Feasibility of patient-reported outcomes collection in clinical routine at a radiotherapy department. [PDF]

Acta Oncol
Fagerström Kristensen I, Linnér A, Nilsson M, Rogowski V, Munck Af Rosenschöld P, Jerkeman M.   +5 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Symptoms, side effects, quality of life and financial toxicity matter to patients with cancer, we need to do a better job of capturing and reporting these concepts in trials and clinical care

BMJ Oncology
Melanie Calvert, Roger Wilson, John Devin Peipert   +2 more
doaj   +1 more source

[Assessment of patient-reported outcomes as an instrument for patient-centered care?] [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Rose M.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A 360 Degree Qualitative Ethical Assessment of Reporting Patient Reported Outcomes. [PDF]

J Empir Res Hum Res Ethics
Huang AP, Corcoran J, Zizzi C, DeFehr C, Contento A, Ross L, Kluger B.   +6 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Digital Intervention for Electronic Patient-Reported Outcomes in Advanced Cancer: Mixed Methods Study. [PDF]

JMIR Cancer
Sauer C, Sauer S, Doll ES, Zschäbitz S, Raue JS, Turni M, Bugaj TJ, Hiller K, Maatouk I.   +8 more
europepmc   +1 more source