Results 191 to 200 of about 3,128,729 (335)

Patient-Reported Outcomes After Single-Stage Spiral Preputial Graft Urethroplasty for Panurethral Strictures: A Single-Centre Prospective Study [PDF]

Saurabh Thakkar, Pankaj Joshi, Shreyas Bhadranavar, Jimena Navarro, Parth Barot, Pawan Kandhari, Sanjay Kulkarni   +6 more
openalex   +1 more source

Editor's Spotlight/Take 5: Readability of Orthopaedic Patient-reported Outcome Measures: Is There a Fundamental Failure to Communicate? [PDF]

, 2017
Montri D. Wongworawat
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Validating Patient-Reported Outcomes and Surveys in Other Languages. [PDF]

Curr Rev Musculoskelet Med
Kwok VE, Diaz A, Grellinger E, Swarup I.
europepmc   +1 more source

SAT0386 Extreme patient reported outcome (PRO) in early spondyloarthritis: a surrogate for fibromyalgia? its impact on TNF-ALPHA blockers treatment effect? [PDF]

, 2017
Bhowmik Meghnathi, Adrien Etcheto, Pascal Claudepierre, M Dougados, Anna Moltó   +4 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Reimagining patient-reported outcomes in the age of generative AI. [PDF]

NPJ Digit Med
Boyer L, Fernandes S, Auquier P, Falissard B, Panch T.   +4 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Sex Differences in Patient-Reported Outcomes Among People Living With HIV Switching to an Oral Dual Therapy: Results From the PROBI Study

AIDS Research and Treatment
Tristan Alain, Fabienne Marcellin, Pascal Bessonneau, Laurent Hocqueloux, Holger Muehlan, Clotilde Allavena, David Zucman, Ester Villalonga-Olives, Olivier Chassany, Martin Duracinsky   +9 more
doaj   +1 more source

Characterizing sleep-related phenotypes with patient-reported outcomes in Parkinson's disease. [PDF]

Front Aging Neurosci
Grover S, Chand C, Acuff MM, Farahnik J, Mischley LK.   +4 more
europepmc   +1 more source