Results 61 to 70 of about 383,023 (311)
The extent, quality and impact of patient and public involvement in primary care research: a mixed methods study [PDF]
, 2018 Background: To improve the lives of patients in primary care requires the involvement of service users in primary care research. We aimed to explore the extent, quality and impact of patient and public involvement (PPI) in primary care research.Methods ...
Jinks
core +1 more source
HRB Open ResearchIntroduction Adults with cerebral palsy (CP) are at increased risk of non-communicable diseases and often experience secondary complications as they age. Physical activity can mitigate these risks and improve well-being.
Karen McConnell +14 more
doaj +1 more source
The 20 m shuttle run is not a valid test of cardiorespiratory fitness in boys aged 11–14 years
BMJ Open Sport & Exercise Medicine, 2019 Objectives The 20 m shuttle run test (20mSRT) is used to estimate cardiorespiratory fitness (CRF) through the prediction of peak oxygen uptake (V˙O2), but its validity as a measure of CRF during childhood and adolescence is questionable.
Jo Welsman, Neil Armstrong
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
HRB Open ResearchIntroduction Adults with cerebral palsy (CP) are at increased risk of non-communicable diseases and often experience secondary complications as they age. Physical activity can mitigate these risks and improve well-being.
Karen McConnell +14 more
doaj +1 more source
What matters most in acute care: an interview study with older people living with frailty
BMC Geriatrics, 2022 Background Healthcare outcome goals are central to person-centred acute care, however evidence among older people is scarce. Older people who are living with frailty have distinct requirements for healthcare delivery and have distinct risk for adverse ...
James David van Oppen +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Patient and public involvement in medical performance processes: A systematic review [PDF]
, 2018 BACKGROUND: Patient and public involvement (PPI) continues to develop as a central policy agenda in health care. The patient voice is seen as relevant, informative and can drive service improvement.
Marshall, Martin +15 more
core +1 more source
Trials, 2018 Background The TRIAL-STIM Study aims to assess the diagnostic performance, clinical outcomes and cost-effectiveness of a screening trial prior to full implantation of a spinal cord stimulation (SCS) device.
Sam Eldabe +14 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source