Results 81 to 90 of about 349,440 (263)

Patient and Public Involvement in Youth Mental Health Research: Protocol for a Systematic Review of Practices and Impact [PDF]

, 2021
Célia M. D. Sales, Filipa Fernandes Martins, Marisa M. Alves, Sara Carletto, Sonia Conejo‐Cerón, Luís Costa da Silva, Anja Čuš, Chloe Edridge, Nuno Ferreira, Camellia Hancheva, Esperanca M. A. Lima, Shaun Liverpool, Nick Midgley, Bettina Moltrecht, Patrícia Moreno-Peral, Nicholas Morgan, Rose Mortimer, Catarina Pinheiro Mota, Giada Pietrabissa, Sónia Sousa, Randi Ulberg, Julian Edbrooke‐Childs   +21 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Co-production as the ultimate goal; an incentive or discouragement?

Research Involvement and Engagement
Patient and public involvement (PPI) in research is a requirement in most of the western world. Funders routinely require extensive PPI plans from applicants and co-production is seen as the ultimate goal.
A. Bangiri, A. Horobin, J. Baker, S. Pszczolkowski, S. Thust, P. S. Morgan   +5 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Public and patient involvement in quantitative health research: A statistical perspective [PDF]

, 2018
Ailish Hannigan
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

P131 Lessons learnt from Patient Public Involvement [PDF]

, 2016
Sarah Cochrane, Michael Clarke, Jackie Haskins, Lucinda Farmer   +3 more
openalex   +1 more source

Engaged genomic science produces better and fairer outcomes: an engagement framework for engaging and involving participants, patients and publics in genomics research and healthcare implementation [PDF]

, 2021
Madeleine J. Murtagh, Mavis Machirori, Clara Gaff, Mwenza Blell, Jantina de Vries, Megan Doerr, Edward S. Dove, Audrey Duncanson, Jillian Hastings Ward, Rachele Hendricks‐Sturrup, Calvin Wai-Loon Ho, Amber L. Johns, Yann Joly, Yoshihiro Kato, Keiko Katsui, Judit Kumuthini, F. Maleady-Crowe, Anna Middleton, Richard Milne, Joel T. Minion, Mogomotsi Matshaba, Stephanie Mulrine, Christine Patch, Rosalyn Ryan, William Viney   +24 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Patient and Public Involvement in Health Economics and Outcomes Research [PDF]

, 2021
Paula Lorgelly
openalex   +1 more source