Results 51 to 60 of about 4,178,246 (299)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

The therapeutic relationship and adherence to antipsychotic medication in schizophrenia [PDF]

, 2012
OBJECTIVE: Previous research has shown that a better therapeutic relationship (TR) predicts more positive attitudes towards antipsychotic medication, but did not address whether it is also linked with actual adherence.
McCabe, R, Hansson Lars, Svensson Bengt, Bullenkamp, J, Rössler, W, Martínez Leal, Rafael, Hansson, Lars, Torres-Gonzalez, F, Lauber, Christoph, Martinez-Leal, Rafael, Durk Wiersma, Roessler, W, Rössler, W., Priebe, Stefan, McCabe, R., Martinez-Leal, R., Svensson, Bengt, Torres González, Francisco, McCabe, Rosemarie, McCabe, Rose, Brink, Rob van den, Rosemarie McCabe, van den Brink Rob, Hansson, Lars,, Hansson, L., Rössler, Wulf, van den Brink, R., Martinez-Leal Rafael, Lars Hansson, Salize, HJ, van den Brink, Rob, Lauber, C., Martinez-Leal, R, Rafael Martinez-Leal, Wiersma Durk, Hans Joachim Salize, Lauber, C, Priebe, S, Lund University., Torres-Gonzalez Francisco, Wiersma, Durk, Torres-Gonzalez, Francisco, Wiersma, D, Rössler Wulf, Priebe, S., Christoph Lauber, Salize, H., Svensson, B., Wiersma, D., Svensson, Bengt,, Rob van den Brink, McCabe Rosemarie, Roessler, Wulf, Priebe Stefan, Jens Bullenkamp, Bullenkamp, J., Stefan Priebe, Francisco Torres-Gonzalez, Bullenkamp, Jens, Bullenkamp Jens, Hansson, L, Lauber Christoph, Salize Hans Joachim, van den Brink, R, Wulf Rössler, Salize, Hans Joachim, Svensson, B, Torres-Gonzalez, F., Bengt Svensson   +68 more
core   +2 more sources

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Special Issue – July/August 2020: Sustaining a Focus on Human Experience in the Face of COVID-19 [PDF]

, 2020
At this critical time in our shared history, we are faced with a powerful challenge, the rapid impact of COVID-19 on our healthcare systems and community.
Journal, Patient Experience, Patient Experience Journal   +1 more
core   +1 more source

Intervention of the family health team on treatment adhesion by hypertension patients

Acta Scientiarum. Health Sciences, 2014
http://dx.doi.org/10.4025/actascihealthsci.v36i1.10376 Current descriptive study with a quantitative approach comprises an analysis of Family Health Teams´ activities on hypertensive users´ treatment adherence, involving 70 professionals from a Family ...
Regina Claúdia Tabosa Ferreira Gomes, Joselany Áfio Caetano, Zélia Maria de Sousa Araújo Santos   +2 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Development and Validation of a Novel General Medication Adherence Scale (GMAS) for Chronic Illness Patients in Pakistan

Frontiers in Pharmacology, 2018
Objective: This study aimed to develop and validate a self-reporting adherence tool termed as General Medication Adherence Scale (GMAS) in Urdu language for measuring adherence toward medication use among Pakistani patients with a chronic disease.Methods:
Atta Abbas Naqvi, Mohamed Azmi Hassali, Mehwish Rizvi, Ale Zehra, Wajiha Iffat, Abdul Haseeb, Shazia Jamshed   +6 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source