Results 61 to 70 of about 1,172,159 (295)

Patient compliance-an overview [PDF]

Journal of Clinical Pharmacy and Therapeutics, 1992
This article reviews the major topic areas of compliance research. Much of the research in the area has focused on measurement, extent, and determinants of non-compliance. Research on the effectiveness of educational and behavioural strategies to improve compliance suggests the need to combine them. While some authors have attempted to model compliance
L S, Morris, R M, Schulz
openaire   +2 more sources

A snapshot of compliance with the sepsis six care bundle in two acute hospitals in the West Midlands, UK [PDF]

, 2019
The sepsis six care bundle has been adopted by hospitals in England and Wales for the management of patients with sepsis, with the aim of increasing survival when all elements of the bundle are achieved.
Frankling, Catriona, Gao, Fang, Melody, Teresa, Patel, Jaimin M., Sharif, Ben, Szakmany, Tamas, Yeung, Joyce   +6 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Intervention of the family health team on treatment adhesion by hypertension patients

Acta Scientiarum. Health Sciences, 2014
http://dx.doi.org/10.4025/actascihealthsci.v36i1.10376 Current descriptive study with a quantitative approach comprises an analysis of Family Health Teams´ activities on hypertensive users´ treatment adherence, involving 70 professionals from a Family ...
Regina Claúdia Tabosa Ferreira Gomes, Joselany Áfio Caetano, Zélia Maria de Sousa Araújo Santos   +2 more
doaj   +1 more source

Improving the Patient Colonoscopy Prep Experience [PDF]

, 2017
AIM: To improve patient prep compliance, prep quality, and an overall better experience by designing a prep specific website that will address the most common prep questions and concerns Once launched, the website address will be placed on printed ...
Cohen, MD, Robert, Cosgrove, MD, Natalie, Dargan, MD, Andrew, Dhanekula, MD, Raja K., Francis, MD, Gloria, Gandhi, MD, Komal, Kistler, MD, Andrew, Malamood, MD, Mark, Moleski, MD, Stephanie M., Niu, MD, Bolin, Prieto, MD, Jorge, Reddy, MD, Sheela S., Shah, MD, Apeksha, Tofani, MD, Christina, Zabolotsky, MD, Andrew   +14 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Compliance, concordance, and patient-centered care

Patient Preference and Adherence, 2011
Sharon LawnFlinders Human Behaviour and Health Research Unit, Margaret Tobin Centre, Flinders University, Adelaide, South AustraliaSince the appearance of the WHO compliance–adherence report1,2 we have had confirmed what many patients and ...
Sharon Lawn
doaj  

Development and Validation of a Novel General Medication Adherence Scale (GMAS) for Chronic Illness Patients in Pakistan

Frontiers in Pharmacology, 2018
Objective: This study aimed to develop and validate a self-reporting adherence tool termed as General Medication Adherence Scale (GMAS) in Urdu language for measuring adherence toward medication use among Pakistani patients with a chronic disease.Methods:
Atta Abbas Naqvi, Mohamed Azmi Hassali, Mehwish Rizvi, Ale Zehra, Wajiha Iffat, Abdul Haseeb, Shazia Jamshed   +6 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source